This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5 DN-Fyn
catalog :
16033
citations: 8
Reference
Wu F, Muskat N, Dvilansky I, Koren O, Shahar A, Gazit R, et al. Acetylation-dependent coupling between G6PD activity and apoptotic signaling. Nat Commun. 2023;14:6208 pubmed publisher
Li W, Chen J, Sun C, Sparks R, Pantano L, Rahman R, et al. Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells. elife. 2022;11: pubmed publisher
St Clair R, Emerson S, D Elia K, Weir M, Schmoker A, Ebert A, et al. Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development. FEBS J. 2018;285:72-86 pubmed publisher
Dustrude E, Moutal A, Yang X, Wang Y, Khanna M, Khanna R. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. Proc Natl Acad Sci U S A. 2016;113:E8443-E8452 pubmed publisher
Ghosh B, Green M, Krogh K, Thayer S. Interleukin-1β activates an Src family kinase to stimulate the plasma membrane Ca2+ pump in hippocampal neurons. J Neurophysiol. 2016;115:1875-85 pubmed publisher
Samovski D, Sun J, Pietka T, Gross R, Eckel R, Su X, et al. Regulation of AMPK activation by CD36 links fatty acid uptake to β-oxidation. Diabetes. 2015;64:353-9 pubmed publisher
Kim A, Lee C, Lee D, Li H, Jeon R, Ryu J, et al. Enhanced antioxidant effect of prenylated polyphenols as Fyn inhibitor. Free Radic Biol Med. 2012;53:1198-208 pubmed publisher
Mariotti A, Kedeshian P, Dans M, Curatola A, Gagnoux Palacios L, Giancotti F. EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell Biol. 2001;155:447-58 pubmed
product information
Catalog Number :
16033
Product Name :
pRK5 DN-Fyn
article :
doi10.1083/jcb.200105017
id1704
pubmed_id11684709
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Fyn
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSLK, SYN, p59-FYN
geneFYN
id2534
genbank_ids
mutationDominant negative: K299M
namec-Fyn
shRNA_sequence
size1700
species
9606
Homo sapiens
tags
resistance markers :
165
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA