This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pGL2-Full
catalog :
16012
citations: 2
Reference
Wang M, LAW M, Davis B, Yaaghubi E, Ghilardi A, Ferreira R, et al. Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway. Cell Death Discov. 2019;5:153 pubmed publisher
Takimoto R, El Deiry W. Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene. 2000;19:1735-43 pubmed
product information
Catalog Number :
16012
Product Name :
pGL2-Full
article :
doi10.1038/sj.onc.1203489
id1691
pubmed_id10777207
bacterial resistance :
Ampicillin
cloning :
backbonepGL2-basic
backbone_mutation
backbone_originPromega
backbone_size5600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
A 3.6 Kb Pst1 fragment from the KILLER/DR5 P1 clone which includes 1.6 Kb upstream of the ATG through Intron 2 in KILLER/DR5 genomic DNA.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5SacI
promoter
sequencing_primer_3LucNrev
sequencing_primer_5EBVrev
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
geneTNFRSF10B
id8795
genbank_ids
mutation
nameKILLER/DR5
shRNA_sequence
size3600
species
9606
Homo sapiens
tags
resistance markers :
129
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA