This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-cmyc
catalog :
16011
citations: 34
Reference
Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, et al. CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion. J Clin Invest. 2023;133: pubmed publisher
Omar F, Brown T, Gillanders W, Fleming T, Smith M, Bremner R, et al. Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1. PLoS ONE. 2023;18:e0285707 pubmed publisher
Walter M, Mayr F, Hanna B, Cookson V, Mortusewicz O, Helleday T, et al. NUDT22 promotes cancer growth through pyrimidine salvage. Oncogene. 2023;42:1282-1293 pubmed publisher
Dos Santos A, Lyu N, Balayan A, Knight R, Zhuo K, Sun Y, et al. Generation of Functional Immortalized Human Corneal Stromal Stem Cells. Int J Mol Sci. 2022;23: pubmed publisher
Xiang W, Qi W, Li H, Sun J, Dong C, Ou H, et al. Palbociclib Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells via RB-Independent STAT3 Phosphorylation. Curr Oncol. 2022;29:5855-5868 pubmed publisher
Haraoka Y, Akieda Y, Nagai Y, Mogi C, Ishitani T. Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis. Nat Commun. 2022;13:1417 pubmed publisher
Fisher M, Balinth S, Hwangbo Y, Wu C, Ballon C, Wilkinson J, et al. BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas. Cancer Res. 2021;81:6246-6258 pubmed publisher
Hassan M, Cwidak N, Johnson C, Däster S, Eppenberger Castori S, Awasthi N, et al. Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer. Front Pharmacol. 2021;12:746385 pubmed publisher
Ghisays F, Garzia A, Wang H, Canasto Chibuque C, Hohl M, Savage S, et al. RTEL1 influences the abundance and localization of TERRA RNA. Nat Commun. 2021;12:3016 pubmed publisher
Ghatak S, Hascall V, Markwald R, Misra S. FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells. Int J Mol Sci. 2021;22: pubmed publisher
Cole A, Iyengar M, Panesso Gómez S, O Hayer P, Chan D, Delgoffe G, et al. NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer. JCI Insight. 2020;5: pubmed publisher
Mishra R, Amanullah A, Upadhyay A, Dhiman R, Dubey A, Singh S, et al. Ubiquitin ligase LRSAM1 suppresses neurodegenerative diseases linked aberrant proteins induced cell death. Int J Biochem Cell Biol. 2020;120:105697 pubmed publisher
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, et al. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Commun. 2019;10:4710 pubmed publisher
Li J, Huang Y, Kuo Y, Cheng C, Kuan F, Chang S, et al. Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence. Cancers (Basel). 2019;11: pubmed publisher
Guo Y, Li H, Guan H, Ke W, Liang W, Xiao H, et al. Dermatopontin inhibits papillary thyroid cancer cell proliferation through MYC repression. Mol Cell Endocrinol. 2019;480:122-132 pubmed publisher
Alidousty C, Baar T, Martelotto L, Heydt C, Wagener S, Fassunke J, et al. Genetic instability and recurrent MYC amplification in ALK-translocated NSCLC: a central role of TP53 mutations. J Pathol. 2018;246:67-76 pubmed publisher
Noguchi K, Dincman T, Dalton A, Howley B, McCall B, Mohanty B, et al. Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1). J Biol Chem. 2018;293:11401-11414 pubmed publisher
Hoppe Seyler K, Honegger A, Bossler F, Sponagel J, Bulkescher J, Lohrey C, et al. Viral E6/E7 oncogene and cellular hexokinase 2 expression in HPV-positive cancer cell lines. Oncotarget. 2017;8:106342-106351 pubmed publisher
Xu L, Li H, Wu L, Huang S. YBX1 promotes tumor growth by elevating glycolysis in human bladder cancer. Oncotarget. 2017;8:65946-65956 pubmed publisher
Luanpitpong S, Angsutararux P, Samart P, Chanthra N, Chanvorachote P, Issaragrisil S. Hyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma. Sci Rep. 2017;7:10607 pubmed publisher
Kim E, Kim A, Kim S, Chang Y. MYC expression correlates with PD-L1 expression in non-small cell lung cancer. Lung Cancer. 2017;110:63-67 pubmed publisher
Tikhanovich I, Zhao J, Bridges B, Kumer S, Roberts B, Weinman S. Arginine methylation regulates c-Myc-dependent transcription by altering promoter recruitment of the acetyltransferase p300. J Biol Chem. 2017;292:13333-13344 pubmed publisher
Chan K, Matchett K, Coulter J, Yuen H, McCrudden C, Zhang S, et al. Erythropoietin drives breast cancer progression by activation of its receptor EPOR. Oncotarget. 2017;8:38251-38263 pubmed publisher
Hahm E, Singh K, Singh S. c-Myc is a novel target of cell cycle arrest by honokiol in prostate cancer cells. Cell Cycle. 2016;15:2309-20 pubmed publisher
Shajahan Haq A, Cook K, Schwartz Roberts J, Eltayeb A, Demas D, Wärri A, et al. MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer. Mol Cancer. 2014;13:239 pubmed publisher
Becker L, Takwi A, Lu Z, Li Y. The role of miR-200a in mammalian epithelial cell transformation. Carcinogenesis. 2015;36:2-12 pubmed publisher
Chhangani D, Upadhyay A, Amanullah A, Joshi V, Mishra A. Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins. Sci Rep. 2014;4:5077 pubmed publisher
Toh P, Luo S, Menzies F, Raskó T, Wanker E, Rubinsztein D. Myc inhibition impairs autophagosome formation. Hum Mol Genet. 2013;22:5237-48 pubmed publisher
Chhangani D, Mishra A. Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity. Sci Rep. 2013;3:1972 pubmed publisher
Kasaai B, Gaumond M, Moffatt P. Regulation of the bone-restricted IFITM-like (Bril) gene transcription by Sp and Gli family members and CpG methylation. J Biol Chem. 2013;288:13278-94 pubmed publisher
Wu I, Shin S, Cao Y, Bender I, Jafari N, Feng G, et al. Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes. Cell Death Dis. 2013;4:e453 pubmed publisher
Takwi A, Li Y, Becker Buscaglia L, Zhang J, Choudhury S, Park A, et al. A statin-regulated microRNA represses human c-Myc expression and function. EMBO Mol Med. 2012;4:896-909 pubmed publisher
Perycz M, Urbanska A, Krawczyk P, Parobczak K, Jaworski J. Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons. J Neurosci. 2011;31:5271-85 pubmed publisher
Ricci M, Jin Z, Dews M, Yu D, Thomas Tikhonenko A, Dicker D, et al. Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity. Mol Cell Biol. 2004;24:8541-55 pubmed
product information
Catalog Number :
16011
Product Name :
pcDNA3-cmyc
article :
doi10.1128/MCB.24.19.8541-8555.2004
id1690
pubmed_id15367674
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Contains cmyc with Kozak.
growth strain :
mammalian expression of human cmyc
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMRTL, MYCC, bHLHe39, c-Myc
geneMYC
id4609
genbank_ids
NM_002467.2
NP_002458.1
mutation
namecmyc
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
129
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA