This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
GFP-RB FL
catalog :
16004
citations: 6
Reference
Miao C, Tsujino T, Takai T, Gui F, Tsutsumi T, Sztupinszki Z, et al. RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer. Sci Adv. 2022;8:eabl9794 pubmed publisher
Pesch A, Hirsh N, Michmerhuizen A, Jungles K, Wilder Romans K, Chandler B, et al. RB expression confers sensitivity to CDK4/6 inhibitor-mediated radiosensitization across breast cancer subtypes. JCI Insight. 2021;: pubmed publisher
Stubbs C, Biancucci M, Vidimar V, Satchell K. RAS specific protease induces irreversible growth arrest via p27 in several KRAS mutant colorectal cancer cell lines. Sci Rep. 2021;11:17925 pubmed publisher
Bechill J, Zhong R, Zhang C, Solomaha E, Spiotto M. A High-Throughput Cell-Based Screen Identified a 2-[(E)-2-Phenylvinyl]-8-Quinolinol Core Structure That Activates p53. PLoS ONE. 2016;11:e0154125 pubmed publisher
Rizzolio F, Lucchetti C, Caligiuri I, Marchesi I, Caputo M, Klein Szanto A, et al. Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1. Cell Death Differ. 2012;19:1152-61 pubmed publisher
Khan M, Brandimarti R, Shimizu S, Nicolai J, Crowe E, Meucci O. The chemokine CXCL12 promotes survival of postmitotic neurons by regulating Rb protein. Cell Death Differ. 2008;15:1663-72 pubmed publisher
product information
Catalog Number :
16004
Product Name :
GFP-RB FL
article :
doi10.1038/cdd.2008.95
id1687
pubmed_id18583990
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C1
backbone_mutation
backbone_originClontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Full length Rb coding sequence, amino acids 1-928. The Rb sequence comprised between sites BamHI and SalI was cloned between BglII and SalI sites in pEGFP-C1.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BglII / BamHI
promoter
sequencing_primer_3
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed1
entrez_gene
aliasesOSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
geneRB1
id5925
genbank_ids
mutation
nameRb
shRNA_sequence
size2784
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagEGFP
resistance markers :
334
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA