This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3 Hygro HA Akt2
catalog :
16000
citations: 6
Reference
Wu X, Zhang Z, Wong J, Rivera Soto R, White M, Rai A, et al. Kaposi's sarcoma-associated herpesvirus viral protein kinase augments cell survival. Cell Death Dis. 2023;14:688 pubmed publisher
Chen M, Choi S, Wen T, Chen C, Thapa N, Lee J, et al. A p53-phosphoinositide signalosome regulates nuclear AKT activation. Nat Cell Biol. 2022;24:1099-1113 pubmed publisher
Shrestha Bhattarai T, Shamu T, Gorelick A, Chang M, Chakravarty D, Gavrila E, et al. AKT mutant allele-specific activation dictates pharmacologic sensitivities. Nat Commun. 2022;13:2111 pubmed publisher
Ratovitski E. Delta Np63 alpha – Responsive microRNA Modulate the Expression of Metabolic Enzymes. Curr Pharm Biotechnol. 2015;16:832-50 pubmed
Kang W, Tong J, Lung R, Dong Y, Yang W, Pan Y, et al. let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis. J Transl Med. 2014;12:281 pubmed publisher
Saoncella S, Tassone B, Deklic E, Avolio F, Jon C, Tornillo G, et al. Nuclear Akt2 opposes limbal keratinocyte stem cell self-renewal by repressing a FOXO-mTORC1 signaling pathway. Stem Cells. 2014;32:754-69 pubmed publisher
product information
Catalog Number :
16000
Product Name :
pcDNA3 Hygro HA Akt2
article :
doi
id1686
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1(+)/Hygro
backbone_mutation
backbone_originInvitrogen
backbone_size5600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
There is a silent mutation at Arg552 (CGA to CGG).
origin :
37
pi :
alt_names
PKBbeta
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRV
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed1
site_5_destroyed
entrez_gene
aliasesHIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
geneAKT2
id208
genbank_ids
M95936
mutation
nameAkt2
shRNA_sequence
size1500
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHA
resistance markers :
37
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA