This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pAMPK alpha2 K45R
catalog :
15992
citations: 16
Reference
Park J, Lee D, Kim D. Redefining the role of AMPK in autophagy and the energy stress response. Nat Commun. 2023;14:2994 pubmed publisher
Liu X, Zhao L, Gao Y, Chen Y, Tian Q, Son J, et al. AMP-activated protein kinase inhibition in fibro-adipogenic progenitors impairs muscle regeneration and increases fibrosis. J Cachexia Sarcopenia Muscle. 2022;: pubmed publisher
Feliciano D, Ott C, Espinosa Medina I, Weigel A, Benedetti L, Milano K, et al. YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion. Nat Commun. 2021;12:4502 pubmed publisher
Kinsey C, Camolotto S, Boespflug A, Guillen K, Foth M, Truong A, et al. Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat Med. 2019;25:620-627 pubmed publisher
Marinangeli C, Didier S, Ahmed T, Caillerez R, Domise M, Laloux C, et al. AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation. iScience. 2018;9:1-13 pubmed publisher
Lee Y, Kim N, Cho E, Yang J, Cha Y, Kang H, et al. Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. Nat Commun. 2018;9:2301 pubmed publisher
Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, et al. Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release. JCI Insight. 2018;3: pubmed publisher
Saha M, Kumar S, Bukhari S, Balaji S, Kumar P, Hindupur S, et al. AMPK-Akt Double-Negative Feedback Loop in Breast Cancer Cells Regulates Their Adaptation to Matrix Deprivation. Cancer Res. 2018;78:1497-1510 pubmed publisher
Hamann J, Surcel A, Chen R, Teragawa C, Albeck J, Robinson D, et al. Entosis Is Induced by Glucose Starvation. Cell Rep. 2017;20:201-210 pubmed publisher
Sato Y, Tsuyama T, Sato C, Karim M, Yoshizawa T, Inoue M, et al. Hypoxia reduces HNF4α/MODY1 protein expression in pancreatic β-cells by activating AMP-activated protein kinase. J Biol Chem. 2017;292:8716-8728 pubmed publisher
Sun X, Yang Q, Rogers C, Du M, Zhu M. AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression. Cell Death Differ. 2017;24:819-831 pubmed publisher
Xue Y, Zhang H, Sun X, Zhu M. Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice. PLoS ONE. 2016;11:e0168670 pubmed publisher
Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, et al. Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity. PLoS ONE. 2015;10:e0130757 pubmed publisher
Weerasekara V, Panek D, Broadbent D, Mortenson J, Mathis A, Logan G, et al. Metabolic-stress-induced rearrangement of the 14-3-3ζ interactome promotes autophagy via a ULK1- and AMPK-regulated 14-3-3ζ interaction with phosphorylated Atg9. Mol Cell Biol. 2014;34:4379-88 pubmed publisher
He H, Liu X, Lv L, Liang H, Leng B, Zhao D, et al. Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress. Cell Death Dis. 2014;5:e997 pubmed publisher
Mu J, Brozinick J, Valladares O, Bucan M, Birnbaum M. A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. Mol Cell. 2001;7:1085-94 pubmed
product information
Catalog Number :
15992
Product Name :
pAMPK alpha2 K45R
article :
doi10.1016/S1097-2765(01)00251-9
id1682
pubmed_id11389854
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
AMPK
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAmpk, Ampka2
genePrkaa2
id78975
genbank_ids
mutationK45R
nameAMPK alpha2
shRNA_sequence
size2000
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tagMyc
plasmid copy :
David Carling, Imperial College School of Medicine
resistance markers :
37
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA