This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pAMPK alpha2 WT
catalog :
15991
citations: 10
Reference
Park J, Lee D, Kim D. Redefining the role of AMPK in autophagy and the energy stress response. Nat Commun. 2023;14:2994 pubmed publisher
Guha P, Tyagi R, Chowdhury S, Reilly L, Fu C, Xu R, et al. IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration. Cell Rep. 2019;26:2692-2703.e7 pubmed publisher
Kinsey C, Camolotto S, Boespflug A, Guillen K, Foth M, Truong A, et al. Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat Med. 2019;25:620-627 pubmed publisher
Marinangeli C, Didier S, Ahmed T, Caillerez R, Domise M, Laloux C, et al. AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation. iScience. 2018;9:1-13 pubmed publisher
Wang S, Wu J, You J, Shi H, Xue X, Huang J, et al. HSF1 deficiency accelerates the transition from pressure overload-induced cardiac hypertrophy to heart failure through endothelial miR-195a-3p-mediated impairment of cardiac angiogenesis. J Mol Cell Cardiol. 2018;118:193-207 pubmed publisher
Sun X, Yang Q, Rogers C, Du M, Zhu M. AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression. Cell Death Differ. 2017;24:819-831 pubmed publisher
Xue Y, Zhang H, Sun X, Zhu M. Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice. PLoS ONE. 2016;11:e0168670 pubmed publisher
Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, et al. Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity. PLoS ONE. 2015;10:e0130757 pubmed publisher
Kazgan N, Williams T, Forsberg L, Brenman J. Identification of a nuclear export signal in the catalytic subunit of AMP-activated protein kinase. Mol Biol Cell. 2010;21:3433-42 pubmed publisher
Mu J, Brozinick J, Valladares O, Bucan M, Birnbaum M. A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. Mol Cell. 2001;7:1085-94 pubmed
product information
Catalog Number :
15991
Product Name :
pAMPK alpha2 WT
article :
doi10.1016/S1097-2765(01)00251-9
id1682
pubmed_id11389854
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
AMPK
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAmpk, Ampka2
genePrkaa2
id78975
genbank_ids
mutation
nameAMPK alpha2
shRNA_sequence
size2000
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tagMyc
plasmid copy :
David Carling, Imperial College School of Medicine
resistance markers :
37
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA