pLEX307-ACE2-blast | Addgene 158449 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pLEX307-ACE2-blast

catalog :

158449

citations: 4

Reference
Duan Y, Zhou H, Liu X, Iketani S, Lin M, Zhang X, et al. Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature. 2023;622:376-382 pubmed publisher
Arshad N, Laurent Rolle M, Ahmed W, Hsu J, Mitchell S, Pawlak J, et al. SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression. Proc Natl Acad Sci U S A. 2023;120:e2208525120 pubmed publisher
Iketani S, Hong S, Sheng J, Bahari F, Culbertson B, Atanaki F, et al. Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites. Cell Host Microbe. 2022;30:1354-1362.e6 pubmed publisher
Liu H, Iketani S, Zask A, Khanizeman N, Bednářová E, Forouhar F, et al. Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nat Commun. 2022;13:1891 pubmed publisher

product information

Catalog Number :

158449

Product Name :

pLEX307-ACE2-blast

article :

doi
id	28215285
pubmed_id

bacterial resistance :

Ampicillin

cloning :

backbone

pLEX307

backbone_mutation

backbone_origin

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Lentiviral

growth strain :

Constitutive lentiviral expression of human ACE2.

origin :

pi :

alt_names

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3	WPRE-R
sequencing_primer_5	EF1a-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ACEH
gene	ACE2
id	59272

genbank_ids

mutation

name

ACE2

shRNA_sequence

size

species

9606

Homo sapiens