This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLENTI_hACE2_HygR
catalog :
155296
citations: 14
Reference
Mazzarella L, Santoro F, Ravasio R, Fumagalli V, Massa P, Rodighiero S, et al. Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses. Sci Signal. 2023;16:eade0326 pubmed publisher
Hossain M, Kerkvliet J, Hoppe A. Whole genome CRISPR screening strategy to identify genes contributing to SARS-CoV-2 spike and VSV-G mediated entry. J Med Virol. 2023;95:e29087 pubmed publisher
Miluzio A, Cuomo A, Cordiglieri C, Donnici L, Pesce E, Bombaci M, et al. Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2. EBioMedicine. 2023;87:104390 pubmed publisher
Song J, Chow R, Pe xf1 a Hern xe1 ndez M, Zhang L, Loeb S, So E, et al. LRRC15 inhibits SARS-CoV-2 cellular entry in trans. PLoS Biol. 2022;20:e3001805 pubmed publisher
Brasu N, Elia I, Russo V, Montacchiesi G, Stabile S, De Intinis C, et al. Memory CD8+ T cell diversity and B cell responses correlate with protection against SARS-CoV-2 following mRNA vaccination. Nat Immunol. 2022;23:1445-1456 pubmed publisher
Compagnone M, Pinto E, Salvatori E, Lione L, Conforti A, Marchese S, et al. DNA-Vaccine-Induced Immune Response Correlates with Lower Viral SARS-CoV-2 Titers in a Ferret Model. Vaccines (Basel). 2022;10: pubmed publisher
Favalli A, Favalli E, Gobbini A, Zagato E, Bombaci M, Maioli G, et al. Immunosuppressant Treatment in Rheumatic Musculoskeletal Diseases Does Not Inhibit Elicitation of Humoral Response to SARS-CoV-2 Infection and Preserves Effector Immune Cell Populations. Front Immunol. 2022;13:873195 pubmed publisher
Andreano E, Paciello I, Marchese S, Donnici L, Pierleoni G, Piccini G, et al. Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees. Nat Commun. 2022;13:3375 pubmed publisher
Torres J, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, et al. Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc Natl Acad Sci U S A. 2022;119:e2120976119 pubmed publisher
Francesconi O, Donnici L, Fragai M, Pesce E, Bombaci M, Fasciani A, et al. Synthetic carbohydrate-binding agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2. iScience. 2022;25:104239 pubmed publisher
Grodzki M, Bluhm A, Schaefer M, Tagmount A, Russo M, Sobh A, et al. Genome-scale CRISPR screens identify host factors that promote human coronavirus infection. Genome Med. 2022;14:10 pubmed publisher
Song J, Chow R, Pena Hernandez M, Zhang L, Loeb S, So E, et al. LRRC15 is an inhibitory receptor blocking SARS-CoV-2 spike-mediated entry in trans. bioRxiv. 2021;: pubmed publisher
Notarbartolo S, Ranzani V, Bandera A, Gruarin P, Bevilacqua V, Putignano A, et al. Integrated longitudinal immunophenotypic, transcriptional and repertoire analyses delineate immune responses in COVID-19 patients. Sci Immunol. 2021;6: pubmed publisher
Neises J, Hossain M, Sultana R, Wanniarachchi K, Wollman J, Nelson E, et al. Seroprevalence of SARS-CoV-2 antibodies among rural healthcare workers. J Med Virol. 2021;: pubmed publisher
product information
Catalog Number :
155296
Product Name :
pLENTI_hACE2_HygR
article :
doi10.1126/sciimmunol.abg5021
id28223116
pubmed_id34376481
bacterial resistance :
Ampicillin
cloning :
backbonepLenti CMV
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Lentiviral
growth strain :
Lentiviral vector to generate hACE2 stable expressing cell line, Hygromycin resistance
inserts :
Stbl3
origin :
30
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5XbaI
promoterCMV
sequencing_primer_3
sequencing_primer_5Unknown
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesACEH
geneACE2
id59272
genbank_ids
mutation
namehACE2
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagC9
resistance markers :
5005
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA