This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMXS-IRES-BLAST co hPHGDH
catalog :
154915
citations: 2
Reference
Ngo B, Kim E, Osorio Vasquez V, Doll S, Bustraan S, Liang R, et al. Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition. Cancer Discov. 2020;10:1352-1373 pubmed publisher
Parakh S, Shadfar S, Perri E, Ragagnin A, Piattoni C, Fogolin M, et al. The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models. iScience. 2020;23:101097 pubmed publisher
product information
Catalog Number :
154915
Product Name :
pMXS-IRES-BLAST co hPHGDH
article :
doi
id28211561
pubmed_id32446203
bacterial resistance :
Ampicillin
cloning :
backbonepMXS-IRES-blast
backbone_mutation
backbone_origin
backbone_size5600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth strain :
Express codon optimized human PHGDH
origin :
37
pi :
alt_names
Phosphoglycerate dehydrogenase
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5EcoRI
promoter
sequencing_primer_3CGGCCTTATTCCAAGCGGCTTCG
sequencing_primer_5AGTAGACGGCATCGCAGCTTGGATA
site_3_destroyed
site_5_destroyed
entrez_gene
aliases3-PGDH, 3PGDH, HEL-S-113, NLS, NLS1, PDG, PGAD, PGD, PGDH, PHGDHD, SERA
genePHGDH
id26227
genbank_ids
mutationCodon optimized for expression in human cells
namePHGDH, codon optimized
shRNA_sequence
size1600
species
9606
Homo sapiens
100
Synthetic
tags
resistance markers :
3646
tags :
High Copy
terms :
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA