This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pK-myc-Par6C
catalog :
15474
citations: 8
Reference
Loo L, Waller M, Moreno C, Cole A, Stella A, Pop O, et al. Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs. PLoS Biol. 2023;21:e3001967 pubmed publisher
Wang L, Rajah A, Brown C, McCaffrey L. CD13 orients the apical-basal polarity axis necessary for lumen formation. Nat Commun. 2021;12:4697 pubmed publisher
Bruurs L, van der Net M, Zwakenberg S, Zwartkruis F, Bos J. A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization. PLoS ONE. 2018;13:e0207159 pubmed publisher
Renschler F, Bruekner S, Salomon P, Mukherjee A, Kullmann L, Schütz Stoffregen M, et al. Structural basis for the interaction between the cell polarity proteins Par3 and Par6. Sci Signal. 2018;11: pubmed publisher
Tobias I, Newton A. Protein Scaffolds Control Localized Protein Kinase C? Activity. J Biol Chem. 2016;291:13809-22 pubmed publisher
Lee S, Zhang W, Ravi M, Weschenfelder M, Bastmeyer M, Levine J. Atypical protein kinase C and Par3 are required for proteoglycan-induced axon growth inhibition. J Neurosci. 2013;33:2541-54 pubmed publisher
Kodani A, Tonthat V, Wu B, Sutterlin C. Par6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitment. Mol Biol Cell. 2010;21:3376-85 pubmed publisher
Joberty G, Petersen C, Gao L, Macara I. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol. 2000;2:531-9 pubmed
product information
Catalog Number :
15474
Product Name :
pK-myc-Par6C
article :
doi10.1038/35019573
id244
pubmed_id10934474
bacterial resistance :
Ampicillin
cloning :
backbonepKmyc
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Par6C
PAR-6C
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoR1
cloning_site_5BamH1
promoter
sequencing_primer_3TTTGTGATGCTATTGCTTTATTTG TA
sequencing_primer_5CAGGTCCAACTGCACCTCGGTTC
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesPAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
genePARD6A
id50855
genbank_ids
AF252292
mutation
namePartitioning-defective protein 6C
shRNA_sequence
size1037
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
resistance markers :
305
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA