This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBabe-GFP-IKBalpha-mut (super repressor)
catalog :
15264
citations: 7
Reference
Roh K, Noh J, Kim Y, Jang Y, Kim J, Choi H, et al. Lysosomal control of senescence and inflammation through cholesterol partitioning. Nat Metab. 2023;5:398-413 pubmed publisher
Ramalingam P, Poulos M, Lazzari E, Gutkin M, Lopez D, Kloss C, et al. Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF. Nat Commun. 2020;11:666 pubmed publisher
Gee T, Farrar E, Wang Y, Wu B, Hsu K, Zhou B, et al. NFκB (Nuclear Factor κ-Light-Chain Enhancer of Activated B Cells) Activity Regulates Cell-Type-Specific and Context-Specific Susceptibility to Calcification in the Aortic Valve. Arterioscler Thromb Vasc Biol. 2020;40:638-655 pubmed publisher
Sha Z, Schnell H, Ruoff K, Goldberg A. Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation. J Cell Biol. 2018;217:1757-1776 pubmed publisher
Poulos M, Ramalingam P, Gutkin M, Kleppe M, Ginsberg M, Crowley M, et al. Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis. Nat Commun. 2016;7:13829 pubmed publisher
Haria D, Trinh B, Ko S, Barengo N, Liu J, Naora H. The homeoprotein DLX4 stimulates NF-?B activation and CD44-mediated tumor-mesothelial cell interactions in ovarian cancer. Am J Pathol. 2015;185:2298-308 pubmed publisher
Boehm J, Zhao J, Yao J, Kim S, Firestein R, Dunn I, et al. Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell. 2007;129:1065-79 pubmed
product information
Catalog Number :
15264
Product Name :
pBabe-GFP-IKBalpha-mut (super repressor)
article :
doi10.1016/j.cell.2007.03.052
id1529
pubmed_id17574021
bacterial resistance :
Ampicillin
cloning :
backbonepBabe-GFP
backbone_mutation
backbone_origin
backbone_size5100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
inhibitor of kappa B alpha
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BglII/BamHI
promoter
sequencing_primer_3
sequencing_primer_5MSCV
site_3_destroyed
site_5_destroyed1
entrez_gene
aliasesEDAID2, IKBA, MAD-3, NFKBI
geneNFKBIA
id4792
genbank_ids
mutationSerine 32 to Alanine, Serine 36 to Alanine
nameIKB alpha
shRNA_sequence
size1000
species
9606
Homo sapiens
tags
resistance markers :
184
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA