This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
IgK-IFN-luc
catalog :
14886
citations: 6
Reference
Salama Y, Takahashi S, Tsuda Y, Okada Y, Hattori K, Heissig B. YO2 Induces Melanoma Cell Apoptosis through p53-Mediated LRP1 Downregulation. Cancers (Basel). 2022;15: pubmed publisher
Jabłońska E, Białopiotrowicz E, Szydłowski M, Prochorec Sobieszek M, Juszczyński P, Szumera Ciećkiewicz A. DEPTOR is a microRNA-155 target regulating migration and cytokine production in diffuse large B-cell lymphoma cells. Exp Hematol. 2020;: pubmed publisher
Claes Z, Jonkhout M, Crespillo Casado A, Bollen M. The antibiotic robenidine exhibits guanabenz-like cytoprotective properties by a mechanism independent of protein phosphatase PP1:PPP1R15A. J Biol Chem. 2019;294:13478-13486 pubmed publisher
Baer A, Colon Moran W, Bhattarai N. Characterization of the effects of immunomodulatory drug fingolimod (FTY720) on human T cell receptor signaling pathways. Sci Rep. 2018;8:10910 pubmed publisher
Cha Molstad H, Sung K, Hwang J, Kim K, Yu J, Yoo Y, et al. Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding. Nat Cell Biol. 2015;17:917-29 pubmed publisher
Pomerantz J, Denny E, Baltimore D. CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex. EMBO J. 2002;21:5184-94 pubmed
product information
Catalog Number :
14886
Product Name :
IgK-IFN-luc
article :
doi10.1093/emboj/cdf505
id1382
pubmed_id12356734
bacterial resistance :
Ampicillin
cloning :
backbonena
backbone_mutation
backbone_origin
backbone_size5800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
Contains two copies of the immunoglobulin kappa light chain kappa-B site (5'-GGGGACTTTCC-3') upstream of the interferon-beta minimal promoter ( 55 to +19) (Fujita et al., 1987) driving luciferase expression.
growth strain :
Reporter construct for NF B activation. Contains two copies of immunoglobulin kappa light chain motif (5 GGGGACTTTCC 3 ) upstream of the a minimal promoter driving luciferase expression
origin :
37
pi :
alt_names
IFNB1
IgK2 IFN LUC reporter
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5SacII
promoter
sequencing_primer_3LucNrev
sequencing_primer_5na
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesIFB, IFF, IFN-beta, IFNB
geneIFNB1
id3456
genbank_ids
mutation
nameIgK-IFN
shRNA_sequence
size80
species
9606
Homo sapiens
tags
resistance markers :
20
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA