This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5 bovine GRK2
catalog :
14691
citations: 5
Reference
Arveseth C, Happ J, Hedeen D, Zhu J, Capener J, Klatt Shaw D, et al. Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. PLoS Biol. 2021;19:e3001191 pubmed publisher
Mayberry C, Wilczek M, Fong T, Nichols S, Maginnis M. GRK2 mediates β-arrestin interactions with 5-HT2 receptors for JC polyomavirus endocytosis. J Virol. 2021;: pubmed publisher
Horiuchi H, Usami A, Shirai R, Harada N, Ikushiro S, Sakaki T, et al. S-Equol Activates cAMP Signaling at the Plasma Membrane of INS-1 Pancreatic β-Cells and Protects against Streptozotocin-Induced Hyperglycemia by Increasing β-Cell Function in Male Mice. J Nutr. 2017;147:1631-1639 pubmed publisher
Clift I, Bamidele A, Rodriguez Ramirez C, Kremer K, Hedin K. ?-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma. Mol Pharmacol. 2014;85:542-52 pubmed publisher
Pitcher J, Tesmer J, Freeman J, Capel W, Stone W, Lefkowitz R. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem. 1999;274:34531-4 pubmed
product information
Catalog Number :
14691
Product Name :
pRK5 bovine GRK2
article :
doi10.1074/jbc.274.49.34531
id1331
pubmed_id10574913
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Using polymerase chain reaction, a 5'
origin :
37
pi :
alt_names
beta adrenergic receptor kinase 1
BARK1
ADRBK1
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5Sp6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADRBK1
geneGRK2
id282682
genbank_ids
mutation
nameGRK2
shRNA_sequence
size2300
species
9913
Bos taurus
tags
resistance markers :
285
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA