This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
RRL.sin.cPPT.SFFV/Ace2.IRES-puro.WPRE (MT126)
catalog :
145839
citations: 11
Reference
Wang Z, Pan Q, Ma L, Zhao J, McIntosh F, Liu Z, et al. Anthracyclines inhibit SARS-CoV-2 infection. Virus Res. 2023;334:199164 pubmed publisher
Ash M, Bhimalli P, Cho B, Mattamana B, Gambut S, Tarhoni I, et al. Bulk IgG glycosylation predicts COVID-19 severity and vaccine antibody response. Cell Rep. 2022;41:111799 pubmed publisher
Forsyth C, Zhang L, Bhushan A, Swanson B, Zhang L, Mamede J, et al. The SARS-CoV-2 S1 Spike Protein Promotes MAPK and NF-kB Activation in Human Lung Cells and Inflammatory Cytokine Production in Human Lung and Intestinal Epithelial Cells. Microorganisms. 2022;10: pubmed publisher
Seo J, Kang B, Song R, Noh H, Kim C, Kim J, et al. Preclinical assessment and randomized Phase I study of CT-P63, a broadly neutralizing antibody targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerg Microbes Infect. 2022;11:2315-2325 pubmed publisher
Patten J, Keiser P, Morselli Gysi D, Menichetti G, Mori H, Donahue C, et al. Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization. iScience. 2022;25:104925 pubmed publisher
Simons L, Ozer E, Gambut S, Dean T, Zhang L, Bhimalli P, et al. De novo emergence of SARS-CoV-2 spike mutations in immunosuppressed patients. Transpl Infect Dis. 2022;24:e13914 pubmed publisher
Jalloh S, Olejnik J, Berrigan J, Nisa A, Suder E, Akiyama H, et al. CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses. bioRxiv. 2022;: pubmed publisher
Ozer E, Simons L, Adewumi O, Fowotade A, Omoruyi E, Adeniji J, et al. Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria. Nat Commun. 2022;13:688 pubmed publisher
Mathieu C, Touret F, Jacquemin C, Janin Y, Nougairede A, Brailly M, et al. A Bioluminescent 3CLPro Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors. Viruses. 2021;13: pubmed publisher
Ozer E, Simons L, Adewumi O, Fowotade A, Omoruyi E, Adeniji J, et al. Coincident rapid expansion of two SARS-CoV-2 lineages with enhanced infectivity in Nigeria. medRxiv. 2021;: pubmed publisher
Rebendenne A, Valadão A, Tauziet M, Maarifi G, Bonaventure B, McKellar J, et al. SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells. J Virol. 2021;: pubmed publisher
product information
Catalog Number :
145839
Product Name :
RRL.sin.cPPT.SFFV/Ace2.IRES-puro.WPRE (MT126)
article :
doi10.1128/JVI.02415-20
id28211215
pubmed_id33514628
bacterial resistance :
Ampicillin
cloning :
backboneRRL.sin.cPPT.SFFV/IRES-puro.WPRE.
backbone_mutation
backbone_originDoyle et al, Nature Microbiology 2018
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth strain :
Lentiviral vector genome to ectopically express human Ace2
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5NotI
promoterSFFV
sequencing_primer_3
sequencing_primer_5
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesACEH
geneACE2
id59272
genbank_ids
mutation
namehuman Ace2
shRNA_sequence
size2418
species
9606
Homo sapiens
tags
plasmid copy :
lentiviral puroR in PMID:30478388 RRL.sin.cPPT.SFFV/IRES-puro.WPRE
resistance markers :
4850
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA