This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLV.ATMi
catalog :
14542
citations: 6
Reference
Suh J, Kim T. A novel DNA double-strand breaks biosensor based on fluorescence resonance energy transfer. Biomater Res. 2023;27:15 pubmed publisher
Priya B, Dubey G, Kirubakaran S. Exploring SPK98 for the Selective Sensitization of ATM- or P53-Deficient Cancer Cells. ACS Omega. 2023;8:4954-4962 pubmed publisher
Ji W, Weng X, Xu D, Cai S, Lou H, Ding L. Non-small cell lung cancer cells with deficiencies in homologous recombination genes are sensitive to PARP inhibitors. Biochem Biophys Res Commun. 2020;522:121-126 pubmed publisher
Wang Y, Xu H, Liu T, Huang M, Butter P, Li C, et al. Temporal DNA-PK activation drives genomic instability and therapy resistance in glioma stem cells. JCI Insight. 2018;3: pubmed publisher
Sinha N, Panda P, Naik P, Das D, Mukhopadhyay S, Maiti T, et al. Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma. Mol Carcinog. 2017;56:2400-2413 pubmed publisher
Ariumi Y, Turelli P, Masutani M, Trono D. DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration. J Virol. 2005;79:2973-8 pubmed
product information
Catalog Number :
14542
Product Name :
pLV.ATMi
article :
doi10.1128/JVI.79.5.2973-2978.2005
id1283
pubmed_id15709017
bacterial resistance :
Ampicillin
cloning :
backbonepRDI292
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
growth notes :
Sense oligo sequence used for cloning: ATM, 5'-GATCCCCGGA TTTGCGTATT ACTCAGTTCA AGAGACTGAG TAATACGCAA ATCCTTTTTG GAAA-3'.
origin :
37
pi :
alt_names
ATM
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5H1
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
geneATM
id472
genbank_ids
mutation
nameATM shRNA
shRNA_sequence
size60
species
9606
Homo sapiens
tags
resistance markers :
532
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA