This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBabe-puro GSK3 beta (S9A)
catalog :
14128
citations: 7
Reference
Flor García M, Avila J, Llorens Martín M. GSK-3β S9A overexpression leads murine hippocampal neural precursors to acquire an astroglial phenotype in vivo. Dev Neurobiol. 2021;81:710-723 pubmed publisher
Fox D, Garcia N, McKinney B, Lupo R, Noteware L, Newcomb R, et al. NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism. Nat Metab. 2020;2:318-334 pubmed publisher
Sun H, Yang W, Tian Y, Zeng X, Zhou J, Mok M, et al. An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma. Nat Commun. 2018;9:5214 pubmed publisher
Elgendy M, Abdel Aziz A, Renne S, Bornaghi V, Procopio G, Colecchia M, et al. Dual modulation of MCL-1 and mTOR determines the response to sunitinib. J Clin Invest. 2017;127:153-168 pubmed publisher
Zheng H, Li W, Wang Y, Liu Z, Cai Y, Xie T, et al. Glycogen synthase kinase-3 beta regulates Snail and ?-catenin expression during Fas-induced epithelial-mesenchymal transition in gastrointestinal cancer. Eur J Cancer. 2013;49:2734-46 pubmed publisher
Kennedy A, McBryan T, Enders G, Johnson F, Zhang R, Adams P. Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci. Cell Div. 2010;5:16 pubmed publisher
Zhang H, Lipovsky A, Dibble C, Sahin M, Manning B. S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt. Mol Cell. 2006;24:185-97 pubmed
product information
Catalog Number :
14128
Product Name :
pBabe-puro GSK3 beta (S9A)
article :
doi10.1016/j.molcel.2006.09.019
id1259
pubmed_id17052453
bacterial resistance :
Ampicillin
cloning :
backbonepBabe-puro
backbone_mutation
backbone_originAvailable at Addgene (#1764)
backbone_size5169
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
pBabe-puro-GSK3 -S9A was generated by standard site-directed mutagenesis from a cDNA clone of human GSK3 .
origin :
37
pi :
alt_names
GSK3b
GSK3beta
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5pBabe 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneGSK3B
id2932
genbank_ids
mutationS9A. Mutant version of GSK3 that lacks the inhibitory phosphorylation site.
nameGSK3 beta (S9A)
shRNA_sequence
size1300
species
9606
Homo sapiens
tags
locationC terminal on insert
tagV5 tag
resistance markers :
309
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA