This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
CS2 Flag-Smad3
catalog :
14052
citations: 6
Reference
El Gazzar A, Kang H, Fratzl Zelman N, Webb E, Barnes A, Jovanovic M, et al. SMAD3 mutation in LDS3 causes bone fragility by impairing the TGF-β pathway and enhancing osteoclastogenesis. Bone Rep. 2022;17:101603 pubmed publisher
Zhou J, Dabiri Y, Gama Brambila R, Ghafoory S, Altinbay M, Mehrabi A, et al. pVHL-mediated SMAD3 degradation suppresses TGF-β signaling. J Cell Biol. 2022;221: pubmed publisher
Cheng X, Haeberle S, Luca Shytaj I, Gama Brambila R, Theobald J, Ghafoory S, et al. NHC-gold compounds mediate immune suppression through induction of AHR-TGFβ1 signalling in vitro and in scurfy mice. Commun Biol. 2020;3:10 pubmed publisher
Tompkins D, Besnard V, Lange A, Wert S, Keiser A, Smith A, et al. Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. PLoS ONE. 2009;4:e8248 pubmed publisher
Lange A, Keiser A, Wells J, Zorn A, Whitsett J. Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium. PLoS ONE. 2009;4:e5711 pubmed publisher
Kretzschmar M, Doody J, Timokhina I, Massague J. A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras. Genes Dev. 1999;13:804-16 pubmed
product information
Catalog Number :
14052
Product Name :
CS2 Flag-Smad3
article :
doi10.1101/gad.13.7.804
id1400
pubmed_id10197981
bacterial resistance :
Ampicillin
cloning :
backbonepCS2
backbone_mutation
backbone_origin
backbone_size4100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Other
xenopus/mammalian/avian/zebrafish
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3EBV rev
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, hMAD-3, hSMAD3, mad3
geneSMAD3
id4088
genbank_ids
mutation
nameSmad3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
313
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA