This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV5 Flag-DPC4
catalog :
14039
citations: 4
Reference
Lanauze C, Sehgal P, Hayer K, Torres Diz M, Pippin J, Grant S, et al. Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4-LEF1 Binding. Mol Cancer Res. 2021;19:823-833 pubmed publisher
Dimitriadis A, Foka P, Kyratzopoulou E, Karamichali E, Petroulia S, Tsitoura P, et al. The Hepatitis C virus NS5A and core proteins exert antagonistic effects on HAMP gene expression: the hidden interplay with the MTF-1/MRE pathway. FEBS Open Bio. 2021;11:237-250 pubmed publisher
Onishi Y, Park G, Iezaki T, Horie T, Kanayama T, Fukasawa K, et al. The transcriptional modulator Ifrd1 is a negative regulator of BMP-2-dependent osteoblastogenesis. Biochem Biophys Res Commun. 2017;482:329-334 pubmed publisher
Lagna G, Hata A, Hemmati Brivanlou A, Massague J. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature. 1996;383:832-6 pubmed
product information
Catalog Number :
14039
Product Name :
pCMV5 Flag-DPC4
article :
doi10.1038/383832a0
id1218
pubmed_id8893010
bacterial resistance :
Ampicillin
cloning :
backbonepCMV5
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Full-length DPC4 with N-terminal Flag tag. See author's map for more information.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5CMV Forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesDPC4, JIP, MADH4, MYHRS
geneSMAD4
id4089
genbank_ids
mutation
nameDPC4
shRNA_sequence
size1700
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
313
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA