This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3 Flag Jnk1a1(apf)
catalog :
13846
citations: 11
Reference
Yang J, Wang J, Liu Y, Zhang Y, Huang W, Zou Y, et al. PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation. Cell Death Dis. 2021;12:707 pubmed publisher
Morgan E, Scarth J, Patterson M, Wasson C, Hemingway G, Barba Moreno D, et al. E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer. Cell Death Differ. 2021;28:1669-1687 pubmed publisher
Valli F, García Vior M, Roguin L, Marino J. Crosstalk between oxidative stress-induced apoptotic and autophagic signaling pathways in Zn(II) phthalocyanine photodynamic therapy of melanoma. Free Radic Biol Med. 2020;152:743-754 pubmed publisher
Pagano C, Siauciunaite R, Idda M, Ruggiero G, Ceinos R, Pagano M, et al. Evolution shapes the responsiveness of the D-box enhancer element to light and reactive oxygen species in vertebrates. Sci Rep. 2018;8:13180 pubmed publisher
Schopp I, Amaya Ramirez C, Debeljak J, Kreibich E, Skribbe M, Wild K, et al. Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes. Nat Commun. 2017;8:15690 pubmed publisher
Park T, Koptyra M, Curran T. Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL). J Biol Chem. 2016;291:26273-26290 pubmed
Wozniak A, Long A, Jones Jamtgaard K, Weinman S. Hepatitis C virus promotes virion secretion through cleavage of the Rab7 adaptor protein RILP. Proc Natl Acad Sci U S A. 2016;113:12484-12489 pubmed
Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher
Schmid C, Robinson M, Scheifinger N, Müller S, Cogliatti S, Tzankov A, et al. DUSP4 deficiency caused by promoter hypermethylation drives JNK signaling and tumor cell survival in diffuse large B cell lymphoma. J Exp Med. 2015;212:775-92 pubmed publisher
Chang Y, Huang Y. Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. PLoS ONE. 2014;9:e107961 pubmed publisher
Derijard B, Hibi M, Wu I, Barrett T, Su B, Deng T, et al. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 1994;76:1025-37 pubmed
product information
Catalog Number :
13846
Product Name :
pCDNA3 Flag Jnk1a1(apf)
article :
doi10.1016/0092-8674(94)90380-8
id1173
pubmed_id8137421
bacterial resistance :
Ampicillin
cloning :
backbonepCDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
MAPK8
cloning
clone_methodRestriction Enzyme
cloning_site_3xbaI
cloning_site_5Hind III
promoter
sequencing_primer_3Sp6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesJNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c
geneMAPK8
id5599
genbank_ids
mutationreplaced dual phosporylation motif Thr(183)-Pro-Tyr(185) with Ala-Pro-Phe
nameJnk1a1(apf)
shRNA_sequence
size1400
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
106
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA