This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pKH3-human RSK1
catalog :
13841
citations: 10
Reference
Park J, Park G, Lee J, Park J, Kim S, Kim E, et al. ERK phosphorylation disrupts the intramolecular interaction of capicua to promote cytoplasmic translocation of capicua and tumor growth. Front Mol Biosci. 2022;9:1030725 pubmed publisher
Asare Y, Campbell James T, Bokov Y, Yu L, Prestel M, El Bounkari O, et al. Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability. Circ Res. 2020;127:811-823 pubmed publisher
Muller L, Rietscher K, Keil R, Neuholz M, Hatzfeld M. Plakophilin 3 phosphorylation by ribosomal S6 kinases supports desmosome assembly. J Cell Sci. 2020;133: pubmed publisher
Moyano Galceran L, Pietilä E, Turunen S, Corvigno S, Hjerpe E, Bulanova D, et al. Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer. EMBO Mol Med. 2020;12:e11177 pubmed publisher
Watanabe D, Nogami A, Okada K, Akiyama H, Umezawa Y, Miura O. FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM. Cancers (Basel). 2019;11: pubmed publisher
Sundell G, Arnold R, Ali M, Naksukpaiboon P, Orts J, Güntert P, et al. Proteome-wide analysis of phospho-regulated PDZ domain interactions. Mol Syst Biol. 2018;14:e8129 pubmed publisher
Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, et al. Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells. PLoS Pathog. 2016;12:e1005660 pubmed publisher
Yang S, Ji M, Zhang L, Chen Y, Wennmann D, Kremerskothen J, et al. Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration. Cell Signal. 2014;26:343-51 pubmed publisher
Hentschke M, Berneking L, Belmar Campos C, Buck F, Ruckdeschel K, Aepfelbacher M. Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation. PLoS ONE. 2010;5: pubmed publisher
Richards S, Dreisbach V, Murphy L, Blenis J. Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1. Mol Cell Biol. 2001;21:7470-80 pubmed
product information
Catalog Number :
13841
Product Name :
pKH3-human RSK1
article :
doi10.1128/MCB.21.21.7470-7480.2001
id347
pubmed_id11585927
bacterial resistance :
Ampicillin
cloning :
backbonepKH3
backbone_mutation
backbone_origin
backbone_size4800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHU-1, MAPKAPK1, MAPKAPK1A, RSK, RSK1, p90Rsk
geneRPS6KA1
id6195
genbank_ids
mutation
nameRSK1
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tag3x HA
resistance markers :
41
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA