This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
HDAC1 Flag
catalog :
13820
citations: 23
Reference
Schwartz L, Bochter M, Simoni A, Bender K, de Dios Ruiz Rosado J, Cotzomi Ortega I, et al. Repurposing HDAC inhibitors to enhance ribonuclease 4 and 7 expression and reduce urinary tract infection. Proc Natl Acad Sci U S A. 2023;120:e2213363120 pubmed publisher
Wang X, Fan D, Han Q, Liu Y, Miao H, Wang X, et al. Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia. Cancer Discov. 2023;13:724-745 pubmed publisher
Harada T, Ohguchi H, Oda A, Nakao M, Teramachi J, Hiasa M, et al. Novel antimyeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase. Blood Adv. 2023;7:1019-1032 pubmed publisher
Bruce J, Bracken M, Evans E, Sherer N, Ahlquist P. ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses. PLoS Pathog. 2021;17:e1009364 pubmed publisher
Pablo Tortola C, Fielitz B, Li Y, Rüdebusch J, Luft F, Fielitz J. Activation of Tripartite Motif Containing 63 Expression by Transcription Factor EB and Transcription Factor Binding to Immunoglobulin Heavy Chain Enhancer 3 Is Regulated by Protein Kinase D and Class IIa Histone Deacetylases. Front Physiol. 2020;11:550506 pubmed publisher
Zhang D, Damoiseaux R, Babayan L, Rivera Meza E, Yang Y, Bergsneider M, et al. Targeting Corticotroph HDAC and PI3-Kinase in Cushing Disease. J Clin Endocrinol Metab. 2021;106:e232-e246 pubmed publisher
Singh V, Pinnamaneni J, Pugazenthi A, Sanagasetti D, Mathison M, Wang K, et al. Enhanced Generation of Induced Cardiomyocytes Using a Small-Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming. J Am Heart Assoc. 2020;9:e015686 pubmed publisher
Mirza A, McKellar S, Urman N, Brown A, Hollmig T, Aasi S, et al. LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription. Cell. 2019;176:198-212.e15 pubmed publisher
Banerjee A, Mahata B, Dhir A, Mandal T, Biswas K. Elevated histone H3 acetylation and loss of the Sp1-HDAC1 complex de-repress the GM2-synthase gene in renal cell carcinoma. J Biol Chem. 2019;294:1005-1018 pubmed publisher
Abdelfattah N, Rajamanickam S, Panneerdoss S, Timilsina S, Yadav P, Onyeagucha B, et al. MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma. Nat Commun. 2018;9:4541 pubmed publisher
Olson H, Jean Marçais N, Yang E, Heron D, Tatton Brown K, van der Zwaag P, et al. A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis. Am J Hum Genet. 2018;102:995-1007 pubmed publisher
Wang Y, Zhang J, Su Y, Shen Y, Jiang D, Hou Y, et al. G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin. Nat Commun. 2017;8:274 pubmed publisher
Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
Burla R, Carcuro M, Torre M, Fratini F, Crescenzi M, D Apice M, et al. The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence. Open Biol. 2016;6: pubmed publisher
Hulin J, Nguyen T, Cui S, Marri S, Yu R, Downes M, et al. Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with ?-Catenin and Chromatin Remodelling. Stem Cells. 2016;34:2169-82 pubmed publisher
Nagesh P, Husain M. Influenza A Virus Dysregulates Host Histone Deacetylase 1 That Inhibits Viral Infection in Lung Epithelial Cells. J Virol. 2016;90:4614-4625 pubmed publisher
Dhar S, Kumar A, Li K, Tzivion G, Levenson A. Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer. Biochim Biophys Acta. 2015;1853:265-75 pubmed publisher
Hsieh I, Liou J, Lee H, Lai M, Li Y, Yang C. Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009. Cell Death Dis. 2014;5:e1166 pubmed publisher
Dzinic S, Kaplun A, Li X, Bernardo M, Meng Y, Dean I, et al. Identification of an intrinsic determinant critical for maspin subcellular localization and function. PLoS ONE. 2013;8:e74502 pubmed publisher
Shin H, Decotiis J, Giron M, Palmeri D, Lukac D. Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation. J Virol. 2014;88:1281-92 pubmed publisher
Buchberger E, El Harchi M, Payrhuber D, Zommer A, Schauer D, Simonitsch Klupp I, et al. Overexpression of the transcriptional repressor complex BCL-6/BCoR leads to nuclear aggregates distinct from classical aggresomes. PLoS ONE. 2013;8:e76845 pubmed publisher
Garcia Garcia J, Barat N, Trembley S, Dumler J. Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum. PLoS Pathog. 2009;5:e1000488 pubmed publisher
Emiliani S, Fischle W, Van Lint C, Al Abed Y, Verdin E. Characterization of a human RPD3 ortholog, HDAC3. Proc Natl Acad Sci U S A. 1998;95:2795-800 pubmed
product information
Catalog Number :
13820
Product Name :
HDAC1 Flag
article :
doi10.1073/pnas.95.6.2795
id1179
pubmed_id9501169
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1 +
backbone_mutation
backbone_originInvitrogen
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
cloned into a version of pcDNA3.1 that has been modified to include a C-terminal Flag tag (see author's map for details).
growth strain :
Mammalian expression of human histone deacetylase 1 with flag tag
origin :
37
pi :
alt_names
Histone Deacetylase 1
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3BGH Reverse
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesGON-10, HD1, KDAC1, RPD3, RPD3L1
geneHDAC1
id3065
genbank_ids
NM_004964
mutation
nameHDAC1
shRNA_sequence
size1600
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagflag
resistance markers :
547
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA