This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
HDAC3 Flag
catalog :
13819
citations: 22
Reference
Maes M, Donahue R, Schlamp C, Marola O, Libby R, Nickells R. BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps. Res Sq. 2023;: pubmed publisher
Garcia Morato J, Hans F, von Zweydorf F, Feederle R, Els xe4 sser S, Skodras A, et al. Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43. Nat Commun. 2022;13:1223 pubmed publisher
Schmitt H, Fehrman R, Maes M, Yang H, Guo L, Schlamp C, et al. Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression. Invest Ophthalmol Vis Sci. 2021;62:14 pubmed publisher
Bruce J, Bracken M, Evans E, Sherer N, Ahlquist P. ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses. PLoS Pathog. 2021;17:e1009364 pubmed publisher
Pablo Tortola C, Fielitz B, Li Y, Rüdebusch J, Luft F, Fielitz J. Activation of Tripartite Motif Containing 63 Expression by Transcription Factor EB and Transcription Factor Binding to Immunoglobulin Heavy Chain Enhancer 3 Is Regulated by Protein Kinase D and Class IIa Histone Deacetylases. Front Physiol. 2020;11:550506 pubmed publisher
Taha T, Anirudhan V, Limothai U, Loeb D, Petukhov P, McLachlan A. Modulation of hepatitis B virus pregenomic RNA stability and splicing by histone deacetylase 5 enhances viral biosynthesis. PLoS Pathog. 2020;16:e1008802 pubmed publisher
Nagareddy B, Khan A, Kim H. Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation. J Biol Chem. 2020;: pubmed publisher
Maes M, Grosser J, Fehrman R, Schlamp C, Nickells R. Completion of BAX recruitment correlates with mitochondrial fission during apoptosis. Sci Rep. 2019;9:16565 pubmed publisher
Choi Y, An S, Bae S, Jung J. Mdm2 is required for HDAC3 monoubiquitination and stability. Biochem Biophys Res Commun. 2019;517:353-358 pubmed publisher
Mirza A, McKellar S, Urman N, Brown A, Hollmig T, Aasi S, et al. LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription. Cell. 2019;176:198-212.e15 pubmed publisher
Wang Y, Zhang J, Su Y, Shen Y, Jiang D, Hou Y, et al. G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin. Nat Commun. 2017;8:274 pubmed publisher
Kwon D, Zhao Y, Lamonica J, Zhou Z. Locus-specific histone deacetylation using a synthetic CRISPR-Cas9-based HDAC. Nat Commun. 2017;8:15315 pubmed publisher
Liu H, Jiang F, Loo Y, Hsu S, Hsiang T, Marcotrigiano J, et al. Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6. EBioMedicine. 2016;9:195-206 pubmed publisher
Yen C, Chen J, Chang Y, Hsu Y, Chiu P, Shiue C, et al. Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade. Sci Rep. 2016;6:25082 pubmed publisher
Cui W, Sun M, Zhang S, Shen X, Galeva N, Williams T, et al. A SUMO-acetyl switch in PXR biology. Biochim Biophys Acta. 2016;1859:1170-1182 pubmed publisher
Huang Y, Huang S, Hsu Y, Ou G, Huang W, Hsu M. The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death. Sci Rep. 2015;5:15900 pubmed publisher
Rahman S, Housein Z, Dabrowska A, Mayán M, Boobis A, Hajji N. E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro. Environ Health Perspect. 2015;123:484-92 pubmed publisher
Bjornsson H, Benjamin J, Zhang L, Weissman J, Gerber E, Chen Y, et al. Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome. Sci Transl Med. 2014;6:256ra135 pubmed publisher
Shin H, Decotiis J, Giron M, Palmeri D, Lukac D. Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation. J Virol. 2014;88:1281-92 pubmed publisher
Buchberger E, El Harchi M, Payrhuber D, Zommer A, Schauer D, Simonitsch Klupp I, et al. Overexpression of the transcriptional repressor complex BCL-6/BCoR leads to nuclear aggregates distinct from classical aggresomes. PLoS ONE. 2013;8:e76845 pubmed publisher
Chang H, Chen C, Hsu Y, Kuo W, Ou G, Chiu P, et al. Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade. Biochim Biophys Acta. 2013;1830:4053-64 pubmed publisher
Emiliani S, Fischle W, Van Lint C, Al Abed Y, Verdin E. Characterization of a human RPD3 ortholog, HDAC3. Proc Natl Acad Sci U S A. 1998;95:2795-800 pubmed
product information
Catalog Number :
13819
Product Name :
HDAC3 Flag
article :
doi10.1073/pnas.95.6.2795
id1179
pubmed_id9501169
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1 +
backbone_mutation
backbone_originInvitrogen
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
cloned into a version of pcDNA3.1 that has been modified to include a C-terminal Flag tag.
growth strain :
Mammalian expression of human histone deacetylase 3 with flag tag
origin :
37
pi :
alt_names
histone deacetylase 3
RPD3
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3BGH Reverse
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHD3, KDAC3, RPD3, RPD3-2
geneHDAC3
id8841
genbank_ids
NM_003883
mutation
nameHDAC3
shRNA_sequence
size1200
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagflag
resistance markers :
547
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA