This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
CDKN1A sgRNA
catalog :
138189
citations: 2
Reference
Kuganesan N, Dlamini S, Tillekeratne L, Taylor W. Tumor suppressor p53 promotes ferroptosis in oxidative stress conditions independent of modulation of ferroptosis by p21, CDKs, RB, and E2F. J Biol Chem. 2021;297:101365 pubmed publisher
Kwan S, Sheel A, Song C, Zhang X, Jiang T, Dang H, et al. Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes. Hepatology. 2019;: pubmed publisher
product information
Catalog Number :
138189
Product Name :
CDKN1A sgRNA
article :
doi10.1002/hep.30807
id28206333
pubmed_id31188495
bacterial resistance :
Ampicillin
cloning :
backboneLentiCRISPRv2 hygro
backbone_mutation
backbone_originBrett Stringer (Addgene plasmid #98291)
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
CRISPR
growth strain :
3rd generation lentiviral gRNA plasmid targeting human CDKN1A
origin :
37
pi :
alt_names
p21
cloning
clone_methodRestriction Enzyme
cloning_site_3BsmB1
cloning_site_5BsmBI
promoterU6
sequencing_primer_3
sequencing_primer_5hU6-F (5'-GAGGGCCTATTTCCCATGATT-3')
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesCAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1
geneCDKN1A
id1026
genbank_ids
NG_009364.1
NM_000389.5
mutation
nameCDKN1A
shRNA_sequenceCACCGTCACCGAGACACCACTGGA
size
species
9606
Homo sapiens
tags
resistance markers :
2401
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA