This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3 RRM2
catalog :
13796
citations: 3
Reference
Rieunier G, Wu X, Harris L, Mills J, Nandakumar A, Colling L, et al. Targeting IGF perturbs global replication through ribonucleotide reductase dysfunction. Cancer Res. 2021;: pubmed publisher
Rasmussen R, Gajjar M, Tučková L, Jensen K, Maya Mendoza A, Holst C, et al. BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity. Nat Commun. 2016;7:13398 pubmed publisher
Duxbury M, Whang E. RRM2 induces NF-kappaB-dependent MMP-9 activation and enhances cellular invasiveness. Biochem Biophys Res Commun. 2007;354:190-6 pubmed
product information
Catalog Number :
13796
Product Name :
pcDNA3 RRM2
article :
doi10.1016/j.bbrc.2006.12.177
id1263
pubmed_id17222798
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1 (+)
backbone_mutation
backbone_originInvitrogen
backbone_size5428
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Ribonucleotide reductase M2 subunit
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5BamHI
promoter
sequencing_primer_3BGH rev primer
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesC2orf48, R2, RR2, RR2M
geneRRM2
id6241
genbank_ids
BC001886
mutation
nameRRM2
shRNA_sequence
size1170
species
9606
Homo sapiens
tags
plasmid copy :
Protein Tech Group, Inc.
resistance markers :
577
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA