This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
SIRT6.27
catalog :
13739
citations: 3
Reference
Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D Angelo C, et al. SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage. Nucleic Acids Res. 2017;45:1820-1834 pubmed publisher
Ronnebaum S, Wu Y, McDonough H, Patterson C. The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination. Mol Cell Biol. 2013;33:4461-72 pubmed publisher
Hallows W, Lee S, Denu J. Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci U S A. 2006;103:10230-10235 pubmed publisher
product information
Catalog Number :
13739
Product Name :
SIRT6.27
article :
doi10.1073/pnas.0604392103
id1144
pubmed_id16790548
bacterial resistance :
Ampicillin
cloning :
backbonepQE-80
backbone_mutation
backbone_originQiagen
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
growth notes :
Full length SIRT6. Molecular Weight: 39120 Da.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5na
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSIR2L6, hSIRT6
geneSIRT6
id51548
genbank_ids
NM_016539
mutation
nameSIRT6
shRNA_sequence
size1100
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHis
resistance markers :
113
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA