This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-EGFP-Rac1(Q61L)
catalog :
13720
citations: 9
Reference
Medina C, Ferreira E, Bonifácio B, Mortara R, Bonfim Melo A. Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages. Microbes Infect. 2021;:104837 pubmed publisher
Li Z, Wang Q, Peng S, Yao K, Chen J, Tao Y, et al. The metastatic promoter DEPDC1B induces epithelial-mesenchymal transition and promotes prostate cancer cell proliferation via Rac1-PAK1 signaling. Clin Transl Med. 2020;10:e191 pubmed publisher
Mo C, Li J, Yang S, Guo H, Liu Y, Luo X, et al. IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma. Br J Cancer. 2020;: pubmed publisher
Lopez Guerrero A, Espinosa Bermejo N, Sanchez Lopez I, MacArtney T, Pascual Caro C, Orantos Aguilera Y, et al. RAC1-Dependent ORAI1 Translocation to the Leading Edge Supports Lamellipodia Formation and Directional Persistence. Sci Rep. 2020;10:6580 pubmed publisher
Bonfim Melo A, Ferreira d, Mortara R. Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. Front Microbiol. 2018;9:360 pubmed publisher
O Loughlin T, Masters T, Buss F. The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics. EMBO Rep. 2018;19: pubmed publisher
Lomakin A, Lee K, Han S, Bui D, Davidson M, Mogilner A, et al. Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization. Nat Cell Biol. 2015;17:1435-45 pubmed publisher
Varela L, Bermudez B, Ortega Gomez A, Lopez S, Sanchez R, Villar J, et al. Postprandial triglyceride-rich lipoproteins promote invasion of human coronary artery smooth muscle cells in a fatty-acid manner through PI3k-Rac1-JNK signaling. Mol Nutr Food Res. 2014;58:1349-64 pubmed publisher
Kraynov V, Chamberlain C, Bokoch G, Schwartz M, Slabaugh S, Hahn K. Localized Rac activation dynamics visualized in living cells. Science. 2000;290:333-7 pubmed
product information
Catalog Number :
13720
Product Name :
pcDNA3-EGFP-Rac1(Q61L)
article :
doi10.1126/science.290.5490.333
id1136
pubmed_id11030651
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Rac1
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMIG5, MRD48, Rac-1, TC-25, p21-Rac1
geneRAC1
id5879
genbank_ids
mutation
nameEGFP-Rac1(Q61L)
shRNA_sequence
size1300
species
9606
Homo sapiens
tags
locationN terminal on insert
tagEGFP
resistance markers :
185
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA