This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-EGFP-Rac1(wt)
catalog :
13719
citations: 11
Reference
Kitzinger R, Fritz G, Henninger C. Nuclear RAC1 is a modulator of the doxorubicin-induced DNA damage response. Biochim Biophys Acta Mol Cell Res. 2022;1869:119320 pubmed publisher
Sasaki S, Takahashi R, Luo Y, Chujo K, Sera T, Kudo S. Spatiotemporal distribution of PKCα, Cdc42, and Rac1 before directed cell migration. Biochem Biophys Res Commun. 2021;584:26-31 pubmed publisher
Medina C, Ferreira E, Bonifácio B, Mortara R, Bonfim Melo A. Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages. Microbes Infect. 2021;:104837 pubmed publisher
Mo C, Li J, Yang S, Guo H, Liu Y, Luo X, et al. IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma. Br J Cancer. 2020;: pubmed publisher
Kuhn S, Bergqvist J, Gil M, Valenzuela C, Barrio L, Lebreton S, et al. Actin Assembly around the Shigella-Containing Vacuole Promotes Successful Infection. Cell Rep. 2020;31:107638 pubmed publisher
Lopez Guerrero A, Espinosa Bermejo N, Sanchez Lopez I, MacArtney T, Pascual Caro C, Orantos Aguilera Y, et al. RAC1-Dependent ORAI1 Translocation to the Leading Edge Supports Lamellipodia Formation and Directional Persistence. Sci Rep. 2020;10:6580 pubmed publisher
Bonfim Melo A, Ferreira d, Mortara R. Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. Front Microbiol. 2018;9:360 pubmed publisher
Lomakin A, Lee K, Han S, Bui D, Davidson M, Mogilner A, et al. Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization. Nat Cell Biol. 2015;17:1435-45 pubmed publisher
Aeberhard L, Banhart S, Fischer M, Jehmlich N, Rose L, Koch S, et al. The Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components. PLoS Pathog. 2015;11:e1004883 pubmed publisher
Sumida G, Yamada S. Rho GTPases and the downstream effectors actin-related protein 2/3 (Arp2/3) complex and myosin II induce membrane fusion at self-contacts. J Biol Chem. 2015;290:3238-47 pubmed publisher
Kraynov V, Chamberlain C, Bokoch G, Schwartz M, Slabaugh S, Hahn K. Localized Rac activation dynamics visualized in living cells. Science. 2000;290:333-7 pubmed
product information
Catalog Number :
13719
Product Name :
pcDNA3-EGFP-Rac1(wt)
article :
doi10.1126/science.290.5490.333
id1136
pubmed_id11030651
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Rac1
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMIG5, MRD48, Rac-1, TC-25, p21-Rac1
geneRAC1
id5879
genbank_ids
mutation
nameEGFP-Rac1(wt)
shRNA_sequence
size1300
species
9606
Homo sapiens
tags
locationN terminal on insert
tagEGFP
resistance markers :
185
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA