This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLNCX chick src Y527F
catalog :
13660
citations: 16
Reference
Kuo M, Yang W, Ho Y, Chang G, Chang H, Hsu C, et al. Hispolon Methyl Ether, a Hispolon Analog, Suppresses the SRC/STAT3/Survivin Signaling Axis to Induce Cytotoxicity in Human Urinary Bladder Transitional Carcinoma Cell Lines. Int J Mol Sci. 2022;24: pubmed publisher
F xe3 o L, Coelho P, Rodrigues R, Rego A. Restored Fyn Levels in Huntington's Disease Contributes to Enhanced Synaptic GluN2B-Composed NMDA Receptors and CREB Activity. Cells. 2022;11: pubmed publisher
Fão L, Mota S, Rego A. c-Src regulates Nrf2 activity through PKCδ after oxidant stimulus. Biochim Biophys Acta Mol Cell Res. 2019;1866:686-698 pubmed publisher
LaFoya B, Munroe J, Pu X, Albig A. Src kinase phosphorylates Notch1 to inhibit MAML binding. Sci Rep. 2018;8:15515 pubmed publisher
Socodato R, Santiago F, Portugal C, Domith I, Encarnação T, Loiola E, et al. Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation. Sci Rep. 2017;7:40912 pubmed publisher
Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, et al. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun. 2016;7:12237 pubmed publisher
Rajala A, Wang Y, Rajala R. Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival. Oncotarget. 2016;7:46924-46942 pubmed publisher
Pal R, Bajaj L, Sharma J, Palmieri M, di Ronza A, Lotfi P, et al. NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's disease. Sci Rep. 2016;6:22866 pubmed publisher
Sancho Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, et al. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nat Commun. 2016;7:10743 pubmed publisher
Gingras J, Gawor M, Bernadzki K, Grady R, Hallock P, Glass D, et al. Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction. J Cell Sci. 2016;129:898-911 pubmed publisher
Lee H, Cheerathodi M, Chaki S, Reyes S, Zheng Y, Lu Z, et al. Protein tyrosine phosphatase-PEST and ?8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells. Mol Cell Biol. 2015;35:1401-13 pubmed publisher
Socodato R, Portugal C, Canedo T, Domith I, Oliveira N, Paes de Carvalho R, et al. c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity. Free Radic Biol Med. 2015;79:45-55 pubmed publisher
Socodato R, Portugal C, Domith I, Oliveira N, Coreixas V, Loiola E, et al. c-Src function is necessary and sufficient for triggering microglial cell activation. Glia. 2015;63:497-511 pubmed publisher
Kathiriya J, Pathak R, Clayman E, Xue B, Uversky V, Dave V. Presence and utility of intrinsically disordered regions in kinases. Mol Biosyst. 2014;10:2876-88 pubmed publisher
Xing W, Liu J, Cheng S, Vogel P, Mohan S, Brommage R. Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis. J Bone Miner Res. 2013;28:1962-74 pubmed publisher
Doherty G, Ahlund M, Howes M, Morén B, Parton R, McMahon H, et al. The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Mol Biol Cell. 2011;22:4380-9 pubmed publisher
product information
Catalog Number :
13660
Product Name :
pLNCX chick src Y527F
article :
doi
id1127
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepLNCX
backbone_mutation
backbone_originBD Biosciences
backbone_size6600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
src
cloning
clone_methodRestriction Enzyme
cloning_site_3ClaI
cloning_site_5ClaI
promoter
sequencing_primer_3
sequencing_primer_5LNCX primer
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesPP60C-SCR, SDR, c-src
geneSRC
id396442
genbank_ids
mutationY527F. Constitutive active mutant.
namesrc Y527F
shRNA_sequence
size1900
species
9031
Gallus gallus
tags
resistance markers :
52
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA