This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLNCX chick src K295R
catalog :
13659
citations: 4
Reference
Pal R, Palmieri M, Chaudhury A, Klisch T, di Ronza A, Neilson J, et al. Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction. Nat Commun. 2018;9:4351 pubmed publisher
Socodato R, Santiago F, Portugal C, Domith I, Encarnação T, Loiola E, et al. Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation. Sci Rep. 2017;7:40912 pubmed publisher
Fianco G, Cenci C, Barilà D. Caspase-8 expression and its Src-dependent phosphorylation on Tyr380 promote cancer cell neoplastic transformation and resistance to anoikis. Exp Cell Res. 2016;347:114-22 pubmed publisher
Socodato R, Portugal C, Domith I, Oliveira N, Coreixas V, Loiola E, et al. c-Src function is necessary and sufficient for triggering microglial cell activation. Glia. 2015;63:497-511 pubmed publisher
product information
Catalog Number :
13659
Product Name :
pLNCX chick src K295R
article :
doi
id1127
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepLNCX
backbone_mutation
backbone_originBD Biosciences
backbone_size6600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
src
cloning
clone_methodRestriction Enzyme
cloning_site_3ClaI
cloning_site_5ClaI
promoter
sequencing_primer_3
sequencing_primer_5LNCX primer
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesPP60C-SCR, SDR, c-src
geneSRC
id396442
genbank_ids
mutationK295R. Kinase dead mutant.
namesrc K295R
shRNA_sequence
size1900
species
9031
Gallus gallus
tags
resistance markers :
52
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA