tet_pLKO.1_puro_shNRF2 #2 | Addgene 136585 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

tet_pLKO.1_puro_shNRF2 #2

catalog :

136585

citations: 4

Reference
Ghosh A, Su Y, Forman M, Keyes R, Smith B, Hu X, et al. Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control. J Virol. 2023;97:e0016023 pubmed publisher
Foley S, Dente M, Lei X, Sallis B, Loew E, Meza Segura M, et al. Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression. MBio. 2022;13:e0199322 pubmed publisher
Gong Z, Xue L, Wei M, Liu Z, Vlantis A, van Hasselt C, et al. The Knockdown of Nrf2 Suppressed Tumor Growth and Increased the Sensitivity to Lenvatinib in Anaplastic Thyroid Cancer. Oxid Med Cell Longev. 2021;2021:3900330 pubmed publisher
Pereira E, Burns J, Lee C, Marohl T, Calderon D, Wang L, et al. Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies. Sci Signal. 2020;13: pubmed publisher

product information

Catalog Number :

136585

Product Name :

tet_pLKO.1_puro_shNRF2 #2

article :

doi	10.1126/scisignal.aba4200
id	28207340
pubmed_id	32291314

bacterial resistance :

Ampicillin

cloning :

backbone

tet-pLKO-puro

backbone_mutation

backbone_origin

Addgene # 21915

backbone_size

10633

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Lentiviral

growth strain :

Expresses an inducible short hairpin targeting human NRF2 sequence

origin :

pi :

sapienstags
Nrf-2geneNFE
2L2id4780d><
/tr>genbank_ids

NM_006164.4

td>mutation<
/tr>nameshNRF2v2<
/tr>shRNA_sequenceGCTC
CTACTGTGATGTGAAATCTGCAGATTTCACATCACAGTA
GGAGCsized>species<
tr>

9606

Homo

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	EcoRI
cloning_site_5	AgeI
promoter
sequencing_primer_3
sequencing_primer_5	GGCAGGGATATTCACCATTATCGTTTCAGA
site_3_destroyed
site_5_destroyed	1

entrez_gene

aliases

HEBP1, IMDDHH, NRF2,

resistance markers :

1585

tags :

Unknown

terms :

Puromycin