This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBABE_hygro_mRFP1_NRF2
catalog :
136579
citations: 3
Reference
Di Giorgio E, Cortolezzis Y, Gualandi N, Agostini F, Rapozzi V, Xodo L. NRF2 interacts with distal enhancer and inhibits nitric oxide synthase 2 expression in KRAS-driven pancreatic cancer cells. Biochim Biophys Acta Mol Cell Res. 2024;1871:119606 pubmed publisher
Di Giorgio E, Choudhary H, Ferino A, Cortolezzis Y, Dalla E, D Este F, et al. Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells. iScience. 2023;26:108566 pubmed publisher
Pereira E, Burns J, Lee C, Marohl T, Calderon D, Wang L, et al. Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies. Sci Signal. 2020;13: pubmed publisher
product information
Catalog Number :
136579
Product Name :
pBABE_hygro_mRFP1_NRF2
article :
doi10.1126/scisignal.aba4200
id28207340
pubmed_id32291314
bacterial resistance :
Ampicillin
cloning :
backbonepBABE-hygro
backbone_mutation
backbone_originAddgene #1765
backbone_size5219
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth strain :
mammalian expression of mRFP1-tagged human NRF2
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5pBABE 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHEBP1, IMDDHH, NRF2, Nrf-2
geneNFE2L2
id4780
genbank_ids
NM_006164
mutation
nameNRF2
shRNA_sequence
size2530
species
9606
Homo sapiens
tags
locationN terminal on insert
tagN-mRFP1-FLAG
resistance markers :
1585
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA