This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3-Flag MKK6
catalog :
13517
citations: 5
Reference
Sellers J, Brooks A, Fernando S, Westenberger G, Junkins S, Smith S, et al. Fasting-Induced Upregulation of MKP-1 Modulates the Hepatic Response to Feeding. Nutrients. 2021;13: pubmed publisher
Rahman S, Zhou W, Deiters A, Haugh J. Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling. J Biol Chem. 2020;295:8494-8504 pubmed publisher
Liu J, Han L, Li B, Yang J, Huen M, Pan X, et al. F-box only protein 31 (FBXO31) negatively regulates p38 mitogen-activated protein kinase (MAPK) signaling by mediating lysine 48-linked ubiquitination and degradation of mitogen-activated protein kinase kinase 6 (MKK6). J Biol Chem. 2014;289:21508-18 pubmed publisher
Ahn Y, Kurie J. MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch. J Biol Chem. 2009;284:29399-404 pubmed publisher
Raingeaud J, Whitmarsh A, Barrett T, Derijard B, Davis R. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol. 1996;16:1247-55 pubmed
product information
Catalog Number :
13517
Product Name :
pCDNA3-Flag MKK6
article :
doi
id1092
pubmed_id8622669
bacterial resistance :
Ampicillin
cloning :
backbonepCDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Xba I
cloning_site_5Hind III
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
geneMAP2K6
id5608
genbank_ids
U39656
mutation
nameMKK6
shRNA_sequence
size1248
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
106
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA