This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBabe puro pI3K p110 CAAX
catalog :
13339
citations: 4
Reference
Malvi P, Chava S, Cai G, Hu K, Zhu L, Edwards Y, et al. HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B. Cell Rep Med. 2023;4:101285 pubmed publisher
Shimizu M, Shibuya H, Tanaka N. Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells. Sci Rep. 2022;12:2910 pubmed publisher
Lee N, Kim I, Park S, Han D, Ha S, Kwon M, et al. Creatine inhibits adipogenesis by downregulating insulin-induced activation of the phosphatidylinositol 3-kinase signaling pathway. Stem Cells Dev. 2015;24:983-94 pubmed publisher
McFall A, Ulku A, Lambert Q, Kusa A, Rogers Graham K, Der C. Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase. Mol Cell Biol. 2001;21:5488-99 pubmed
product information
Catalog Number :
13339
Product Name :
pBabe puro pI3K p110 CAAX
article :
doi10.1128/MCB.21.16.5488-5499.2001
id928
pubmed_id11463831
bacterial resistance :
Ampicillin
cloning :
backbonepBabe puro
backbone_mutation
backbone_origin
backbone_size5169
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
Plasma membrane-targeted, constitutively activated PI3K p110. Please note that the myc tag is NONFUNCTIONAL.
origin :
37
pi :
alt_names
pI3K
p110
PIK3CA
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5BamHI
promoter
sequencing_primer_3pBabe 3'
sequencing_primer_5pBabe 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
genePIK3CA
id282306
genbank_ids
NM_174574
mutation
namepI3K p110 CAAX
shRNA_sequence
size3200
species
9913
Bos taurus
tags
resistance markers :
114
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA