This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLenti6-DEST PINK1-V5 WT
catalog :
13320
citations: 8
Reference
Fessler E, Krumwiede L, Jae L. DELE1 tracks perturbed protein import and processing in human mitochondria. Nat Commun. 2022;13:1853 pubmed publisher
Uesugi R, Ishii S, Matsuura A, Itakura E. Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor. J Biol Chem. 2021;297:101279 pubmed publisher
Yin K, Lee J, Liu Z, Kim H, Martin D, Wu D, et al. Mitophagy protein PINK1 suppresses colon tumor growth by metabolic reprogramming via p53 activation and reducing acetyl-CoA production. Cell Death Differ. 2021;28:2421-2435 pubmed publisher
Yang R, Tao J, Zhan M, Yuan H, Wang H, Chen S, et al. TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Cell Death Differ. 2019;: pubmed publisher
Safiulina D, Kuum M, Choubey V, Gogichaishvili N, Liiv J, Hickey M, et al. Miro proteins prime mitochondria for Parkin translocation and mitophagy. EMBO J. 2019;38: pubmed publisher
Bartolomé A, García Aguilar A, Asahara S, Kido Y, Guillen C, Pajvani U, et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol. 2017;37: pubmed publisher
Sinnen B, Bowen A, Forte J, Hiester B, Crosby K, Gibson E, et al. Optogenetic Control of Synaptic Composition and Function. Neuron. 2017;93:646-660.e5 pubmed publisher
Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller D, Petsko G, et al. Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proc Natl Acad Sci U S A. 2005;102:5703-8 pubmed
product information
Catalog Number :
13320
Product Name :
pLenti6-DEST PINK1-V5 WT
article :
doi10.1073/pnas.0500617102
id1025
pubmed_id15824318
bacterial resistance :
Ampicillin
cloning :
backbonepLenti6/V5-DEST
backbone_mutation
backbone_originInvitrogen
backbone_size8688
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
origin :
37
pi :
alt_names
cloning
clone_methodGateway Cloning
cloning_site_3attR2
cloning_site_5attR1
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBRPK, PARK6
genePINK1
id65018
genbank_ids
mutation
namePINK1
shRNA_sequence
size1743
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagV5
resistance markers :
89
tags :
High Copy
terms :
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA