This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCI-Neo-gp78 R2M / JM21
catalog :
13304
citations: 3
Reference
Chang Y, Tseng C, Wang M, Chang W, Lee C, Chen L, et al. Deacetylation of HSPA5 by HDAC6 leads to GP78-mediated HSPA5 ubiquitination at K447 and suppresses metastasis of breast cancer. Oncogene. 2016;35:1517-28 pubmed publisher
Chang Y, Chen H, Tseng C, Hong C, Ma J, Hung M, et al. De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells. Oncotarget. 2014;5:10558-70 pubmed
Fang S, Ferrone M, Yang C, Jensen J, Tiwari S, Weissman A. The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proc Natl Acad Sci U S A. 2001;98:14422-7 pubmed
product information
Catalog Number :
13304
Product Name :
pCI-Neo-gp78 R2M / JM21
article :
doi10.1073/pnas.251401598
id549
pubmed_id11724934
bacterial resistance :
Ampicillin
cloning :
backbonepCI-neo
backbone_mutation
backbone_originPromega
backbone_size5472
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
AMFR
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5XhoI
promoter
sequencing_primer_3T3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesGP78, RNF45
geneAMFR
id267
genbank_ids
NM_001144
mutationC356G ; H362A
namegp78
shRNA_sequence
size1900
species
9606
Homo sapiens
tags
resistance markers :
571
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA