MigR1-Flag-TRIB3 | Addgene 131159 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

MigR1-Flag-TRIB3

catalog :

131159

citations: 2

Reference
Nyati K, Hashimoto S, Singh S, Tekguc M, Metwally H, Liu Y, et al. The novel long noncoding RNA AU021063, induced by IL-6/Arid5a signaling, exacerbates breast cancer invasion and metastasis by stabilizing Trib3 and activating the Mek/Erk pathway. Cancer Lett. 2021;: pubmed publisher
Dedhia P, Keeshan K, ULJON S, Xu L, Vega M, Shestova O, et al. Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia. Blood. 2010;116:1321-8 pubmed publisher

product information

Catalog Number :

131159

Product Name :

MigR1-Flag-TRIB3

article :

doi	10.1182/blood-2009-07-229450
id	28203983
pubmed_id	20410507

bacterial resistance :

Ampicillin

cloning :

backbone

MIGR1

backbone_mutation

backbone_origin

Warren Pear (Addgene plasmid # 27490)

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Retroviral

growth notes :

Trib3 contains a N201T mismatch located within the pseudokinase domain but out-with core motif. Both Asparagine and Threonine are polar and form hydrogen bonds as both donors and acceptors; substitution should have minimal effect on protein structure/function.

growth strain :

Retroviral expression of flag-tagged mouse TRIB3

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	Unknown
cloning_site_5	Unknown
promoter
sequencing_primer_3
sequencing_primer_5
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	Ifld2, Nipk, SINK, SKIP3, TRB-3, Trb3
gene	Trib3
id	228775

genbank_ids

mutation

name

Trib3

shRNA_sequence

size

species

10090

Mus musculus