This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
hTLR3 flag
catalog :
13084
citations: 6
Reference
Chen K, Yu C, Kung S, Chen S, Chang C, Ho T, et al. Toll-Like Receptor 3 Is Involved in Detection of Enterovirus A71 Infection and Targeted by Viral 2A Protease. Viruses. 2018;10: pubmed publisher
Bugge M, Bergstrom B, Eide O, Solli H, Kjønstad I, Stenvik J, et al. Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness. J Biol Chem. 2017;292:15408-15425 pubmed publisher
Chauhan S, Mandell M, Deretic V. IRGM governs the core autophagy machinery to conduct antimicrobial defense. Mol Cell. 2015;58:507-21 pubmed publisher
Cheng J, Sun Y, Zhang X, Zhang F, Zhang S, Yu S, et al. Toll-like receptor 3 inhibits Newcastle disease virus replication through activation of pro-inflammatory cytokines and the type-1 interferon pathway. Arch Virol. 2014;159:2937-48 pubmed publisher
Setta Kaffetzi N, Simpson M, Navarini A, Patel V, Lu H, Allen M, et al. AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking. Am J Hum Genet. 2014;94:790-7 pubmed publisher
Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, Quintana F, et al. Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway. J Exp Med. 2009;206:1661-71 pubmed publisher
product information
Catalog Number :
13084
Product Name :
hTLR3 flag
article :
doi
id998
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepFlag-CMV-1
backbone_mutation
backbone_originSigma
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
toll-like receptor 3
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5HindIII
promoter
sequencing_primer_3CMV24
sequencing_primer_5CMV30
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD283, IIAE2, IMD83
geneTLR3
id7098
genbank_ids
NM_003265
mutationAmino acids 1-17 have been replaced by mammalian signal sequence (SALLILALVGAAVA) followed by FLAG tag
nameTLR3
shRNA_sequence
size2700
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagFlag
resistance markers :
325
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA