This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-TLR4-YFP
catalog :
13018
citations: 15
Reference
Sun P, Li D, Su M, Ren Q, Guo W, Wang J, et al. Cell membrane-bound toll-like receptor-1/2/4/6 monomers and -2 heterodimer inhibit enterovirus 71 replication by activating the antiviral innate response. Front Immunol. 2023;14:1187035 pubmed publisher
Muusse T, Lee M, Kim H, Parat M, Nanson J, Kobe B, et al. Flow cytometric reporter assays provide robust functional analysis of signaling complexes. J Biol Chem. 2022;298:102666 pubmed publisher
Wang W, Demaurex N. The mammalian trafficking chaperone protein UNC93B1 maintains the ER calcium sensor STIM1 in a dimeric state primed for translocation to the ER cortex. J Biol Chem. 2022;298:101607 pubmed publisher
Poncin M, Van Meerbeeck P, Simpson J, Clippe A, Tyckaert F, Bouillenne F, et al. Role of the Redox State of Human Peroxiredoxin-5 on Its TLR4-Activating DAMP Function. Antioxidants (Basel). 2021;10: pubmed publisher
Hassan M, Keller M, Hillger M, Binder U, Reuter S, Herold K, et al. The impact of episporic modification of Lichtheimia corymbifera on virulence and interaction with phagocytes. Comput Struct Biotechnol J. 2021;19:880-896 pubmed publisher
Moraes Vieira P, Yore M, Sontheimer Phelps A, Castoldi A, Norseen J, Aryal P, et al. Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4. Proc Natl Acad Sci U S A. 2020;117:31309-31318 pubmed publisher
Choi I, Zhang Y, Seegobin S, Pruvost M, Wang Q, Purtell K, et al. Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration. Nat Commun. 2020;11:1386 pubmed publisher
Tapader R, Bose D, Dutta P, Das S, Pal A. SslE (YghJ), a Cell-Associated and Secreted Lipoprotein of Neonatal Septicemic Escherichia coli, Induces Toll-Like Receptor 2-Dependent Macrophage Activation and Proinflammation through NF-κB and MAP Kinase Signaling. Infect Immun. 2018;86: pubmed publisher
Knoops B, Becker S, Poncin M, Glibert J, Derclaye S, Clippe A, et al. Specific Interactions Measured by AFM on Living Cells between Peroxiredoxin-5 and TLR4: Relevance for Mechanisms of Innate Immunity. Cell Chem Biol. 2018;25:550-559.e3 pubmed publisher
Alvarado A, Thiagarajan P, Mulkearns Hubert E, Silver D, Hale J, Alban T, et al. Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression. Cell Stem Cell. 2017;20:450-461.e4 pubmed publisher
Chauhan S, Mandell M, Deretic V. IRGM governs the core autophagy machinery to conduct antimicrobial defense. Mol Cell. 2015;58:507-21 pubmed publisher
Moncayo Nieto O, Wilkinson T, Brittan M, McHugh B, Jones R, Conway Morris A, et al. Differential response to bacteria, and TOLLIP expression, in the human respiratory tract. BMJ Open Respir Res. 2014;1:e000046 pubmed publisher
Chesarino N, Hach J, Chen J, Zaro B, Rajaram M, Turner J, et al. Chemoproteomics reveals Toll-like receptor fatty acylation. BMC Biol. 2014;12:91 pubmed publisher
Kiyan Y, Tkachuk S, Hilfiker Kleiner D, Haller H, Fuhrman B, Dumler I. oxLDL induces inflammatory responses in vascular smooth muscle cells via urokinase receptor association with CD36 and TLR4. J Mol Cell Cardiol. 2014;66:72-82 pubmed publisher
Stewart C, Stuart L, Wilkinson K, van Gils J, Deng J, Halle A, et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol. 2010;11:155-61 pubmed publisher
product information
Catalog Number :
13018
Product Name :
pcDNA3-TLR4-YFP
article :
doi
id978
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3-YFP
backbone_mutation
backbone_origin
backbone_size6100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
The primer for sequencing out the 5' end of the GFP based constructs (GFP/EGFP, CFP, YFP) is 5'- GTCTTGTAGTTGCCGTCGTC -3'
origin :
37
pi :
alt_names
TLR4
TOLL
CD284
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5BamHI
promoter
sequencing_primer_3GTCTTGTAGTTGCCGTCGTC
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesARMD10, CD284, TLR-4, TOLL
geneTLR4
id7099
genbank_ids
BC117422
mutation
nameToll-Like Receptor 4
shRNA_sequence
size2517
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagYFP
resistance markers :
169
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA