This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
IRE1 alpha-pcDNA3.EGFP
catalog :
13009
citations: 11
Reference
Wang G, Song S, Shen W, Reece E, Yang P. microRNA-322 overexpression reduces neural tube defects in diabetic pregnancies. Am J Obstet Gynecol. 2023;: pubmed publisher
Zhang Y, Wang Y, Zhao G, Tanner E, Adli M, Matei D. FOXK2 promotes ovarian cancer stemness by regulating the unfolded protein response pathway. J Clin Invest. 2022;132: pubmed publisher
Blanchard T, Lapidus R, Banerjee V, Bafford A, Czinn S, Ahmed H, et al. Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation. Cell Physiol Biochem. 2018;48:1259-1273 pubmed publisher
Su A, Wang H, Li Y, Wang X, Chen D, Wu Z. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication. Viruses. 2017;9: pubmed publisher
Tufanlı Ö, Telkoparan Akillilar P, Acosta Alvear D, Kocatürk B, Onat U, Hamid S, et al. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc Natl Acad Sci U S A. 2017;114:E1395-E1404 pubmed publisher
Cagalinec M, Liiv M, Hodurova Z, Hickey M, Vaarmann A, Mandel M, et al. Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. PLoS Biol. 2016;14:e1002511 pubmed publisher
Banerjee A, Ahmed H, Yang P, Czinn S, Blanchard T. Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment. Oncotarget. 2016;7:41432-41444 pubmed publisher
Shigemi Z, Baba Y, Hara N, Matsuhiro J, Kagawa H, Watanabe T, et al. Effects of ER stress on unfolded protein responses, cell survival, and viral replication in primary effusion lymphoma. Biochem Biophys Res Commun. 2016;469:565-72 pubmed publisher
Plumb R, Zhang Z, Appathurai S, Mariappan M. A functional link between the co-translational protein translocation pathway and the UPR. elife. 2015;4: pubmed publisher
Nguyen T, Grant S. Dinaciclib (SCH727965) inhibits the unfolded protein response through a CDK1- and 5-dependent mechanism. Mol Cancer Ther. 2014;13:662-74 pubmed publisher
Lipson K, Fonseca S, Ishigaki S, Nguyen L, Foss E, Bortell R, et al. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab. 2006;4:245-54 pubmed
product information
Catalog Number :
13009
Product Name :
IRE1 alpha-pcDNA3.EGFP
article :
doi10.1016/j.cmet.2006.07.007
id976
pubmed_id16950141
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3-EGFP
backbone_mutation
backbone_origin
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
IRE1
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5HindIII
promoter
sequencing_primer_3Sp6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesIRE1, IRE1P, IRE1a, hIRE1p
geneERN1
id2081
genbank_ids
mutation
nameInositol Requiring Enzyme-1
shRNA_sequence
size3500
species
9606
Homo sapiens
tags
plasmid copy :
cDNA is from Dr. Randy Kaufman at the University of Michigan. The vector is from Dr. David Ron at the New York University School of Medicine.
resistance markers :
540
tags :
High Copy
terms :
Other
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA