This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5-myc-Rac1-Q61L
catalog :
12983
citations: 5
Reference
Canales J, Cruz P, Diaz N, Riquelme D, Leiva Salcedo E, Cerda O. K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and Spreading through Modulation of Ca2+ Signaling and Rac1 Activity. Cells. 2020;9: pubmed publisher
Mendoza Topaz C, Yeow I, Riento K, Nichols B. BioID identifies proteins involved in the cell biology of caveolae. PLoS ONE. 2018;13:e0209856 pubmed publisher
Zhou H, Cai L, Zhang X, Li A, Miao Y, Li Q, et al. ARHGEF39 promotes tumor progression via activation of Rac1/P38 MAPK/ATF2 signaling and predicts poor prognosis in non-small cell lung cancer patients. Lab Invest. 2018;98:670-681 pubmed publisher
Kajimoto T, Mohamed N, Badawy S, Matovelo S, Hirase M, Nakamura S, et al. Involvement of Gβγ subunits of Gi protein coupled with S1P receptor on multivesicular endosomes in F-actin formation and cargo sorting into exosomes. J Biol Chem. 2018;293:245-253 pubmed publisher
Manchanda P, Jones G, Lee A, Pringle D, Zhang M, Yu L, et al. Rac1 is required for Prkar1a-mediated Nf2 suppression in Schwann cell tumors. Oncogene. 2013;32:3491-9 pubmed publisher
product information
Catalog Number :
12983
Product Name :
pRK5-myc-Rac1-Q61L
article :
doi
id965
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepRK5-Myc
backbone_mutation
backbone_origin
backbone_size4750
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Rac1
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMIG5, MRD48, Rac-1, TC-25, p21-Rac1
geneRAC1
id5879
genbank_ids
AF498964
mutationQ61L Constitutively active
nameRac1 constitutively active
shRNA_sequence
size579
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
resistance markers :
45
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA