This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5-myc-Cdc42-T17N
catalog :
12973
citations: 7
Reference
Dehapiot B, Clément R, Bourdais A, Carriere V, Huet S, Halet G. RhoA- and Cdc42-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes. PLoS Biol. 2021;19:e3001376 pubmed publisher
Kim J, Kang W, Kang S, Park S, Kim J, Yang S, et al. Proline-rich tyrosine kinase 2 mediates transforming growth factor-beta-induced hepatic stellate cell activation and liver fibrosis. Sci Rep. 2020;10:21018 pubmed publisher
Morgan C, Hedman A, Li Z, Sacks D. Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras. Sci Rep. 2019;9:11057 pubmed publisher
Razidlo G, Burton K, McNiven M. Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem. 2018;293:11143-11153 pubmed publisher
Cao H, Eppinga R, Razidlo G, Krueger E, Chen J, Qiang L, et al. Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process. Oncogene. 2016;35:1099-1110 pubmed publisher
Dehapiot B, Halet G. Ran GTPase promotes oocyte polarization by regulating ERM (Ezrin/Radixin/Moesin) inactivation. Cell Cycle. 2013;12:1672-8 pubmed publisher
Dehapiot B, Carriere V, Carroll J, Halet G. Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes. Dev Biol. 2013;377:202-12 pubmed publisher
product information
Catalog Number :
12973
Product Name :
pRK5-myc-Cdc42-T17N
article :
doi
id965
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepRK5-Myc
backbone_mutation
backbone_origin
backbone_size4750
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Cdc42
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCDC42Hs, G25K, TKS
geneCDC42
id998
genbank_ids
M57298
mutationT17N Dominant negative
nameCdc42 DN
shRNA_sequence
size576
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
plasmid copy :
P. Hall
resistance markers :
45
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA