This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5-myc-RhoA-T19N
catalog :
12963
citations: 5
Reference
McCray B, Diehl E, Sullivan J, Aisenberg W, Zaccor N, Lau A, et al. Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. Nat Commun. 2021;12:1444 pubmed publisher
Kim J, Kang W, Kang S, Park S, Kim J, Yang S, et al. Proline-rich tyrosine kinase 2 mediates transforming growth factor-beta-induced hepatic stellate cell activation and liver fibrosis. Sci Rep. 2020;10:21018 pubmed publisher
Zhang S, Chatterjee T, Godoy C, Wu L, Liu Q, Carmon K. GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism. Mol Cancer Res. 2019;17:2196-2207 pubmed publisher
Lee S, Salazar S, Cox T, Strittmatter S. Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss. J Neurosci. 2019;39:1910-1929 pubmed publisher
Wong A, Loots G, Yellowley C, Dosé A, Genetos D. Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells. Bone. 2015;81:97-103 pubmed publisher
product information
Catalog Number :
12963
Product Name :
pRK5-myc-RhoA-T19N
article :
doi
id965
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepRK5-Myc
backbone_mutation
backbone_origin
backbone_size4750
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
RhoA
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesARH12, ARHA, EDFAOB, RHO12, RHOH12
geneRHOA
id387
genbank_ids
L25080
mutationT19N Dominant negative
nameRhoA DN
shRNA_sequence
size582
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
plasmid copy :
P. Hall
resistance markers :
45
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA