This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LentiCRISPR v2 hBAX
catalog :
129580
citations: 4
Reference
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli M, Riley J, et al. Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature. 2023;622:627-636 pubmed publisher
Luanpitpong S, Janan M, Yosudjai J, Poohadsuan J, Chanvorachote P, Issaragrisil S. Bcl-2 Family Members Bcl-xL and Bax Cooperatively Contribute to Bortezomib Resistance in Mantle Cell Lymphoma. Int J Mol Sci. 2022;23: pubmed publisher
Payapilly A, Guilbert R, Descamps T, White G, Magee P, Zhou C, et al. TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change. Cell Rep. 2021;37:109979 pubmed publisher
Lopez J, Bessou M, Riley J, Giampazolias E, Todt F, Rochegüe T, et al. Mito-priming as a method to engineer Bcl-2 addiction. Nat Commun. 2016;7:10538 pubmed publisher
product information
Catalog Number :
129580
Product Name :
LentiCRISPR v2 hBAX
article :
doi10.1038/ncomms10538
id20875
pubmed_id26833356
bacterial resistance :
Ampicillin
cloning :
backbonepLentiCRISPRv2
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth strain :
CRISPR deletion of human BAX
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Unknown
cloning_site_5Unknown
promoter
sequencing_primer_3
sequencing_primer_5
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCL2L4
geneBAX
id581
genbank_ids
mutationNone
namegRNA vs human BAX
shRNA_sequenceAGTAGAAAAGGGCGACAACC
size
species
9606
Homo sapiens
tags
resistance markers :
2195
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA