This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LNCX TbetaRII DN
catalog :
12640
citations: 2
Reference
Yousef H, Conboy M, Morgenthaler A, Schlesinger C, Bugaj L, Paliwal P, et al. Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. Oncotarget. 2015;6:11959-78 pubmed
Choy L, Skillington J, Derynck R. Roles of autocrine TGF-beta receptor and Smad signaling in adipocyte differentiation. J Cell Biol. 2000;149:667-82 pubmed
product information
Catalog Number :
12640
Product Name :
LNCX TbetaRII DN
article :
doi10.1083/jcb.149.3.667
id943
pubmed_id10791980
bacterial resistance :
Ampicillin
cloning :
backboneLNCX
backbone_mutation
backbone_origin
backbone_size6600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HpaI
cloning_site_5HpaI
promoter
sequencing_primer_3
sequencing_primer_5LNCX
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesAAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII, tbetaR-II
geneTGFBR2
id7048
genbank_ids
mutationDominant negative: truncated cytoplasmically
nameTGF-beta receptor II
shRNA_sequence
size600
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFlag
resistance markers :
115
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA