This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LPCX Smad3
catalog :
12638
citations: 5
Reference
Huna A, Flaman J, Lodillinsky C, Zhu K, Makulyte G, Pakulska V, et al. RSK3 switches cell fate: from stress-induced senescence to malignant progression. J Exp Clin Cancer Res. 2023;42:318 pubmed publisher
Bryson B, Junk D, Cipriano R, Jackson M. STAT3-mediated SMAD3 activation underlies Oncostatin M-induced Senescence. Cell Cycle. 2017;16:319-334 pubmed publisher
Zhou H, Chen L, Liang H, Li G, Zhang B, Chen X. Smad3 Sensitizes Hepatocelluar Carcinoma Cells to Cisplatin by Repressing Phosphorylation of AKT. Int J Mol Sci. 2016;17: pubmed publisher
Marchildon F, St Louis C, Akter R, Roodman V, Wiper Bergeron N. Transcription factor Smad3 is required for the inhibition of adipogenesis by retinoic acid. J Biol Chem. 2010;285:13274-84 pubmed publisher
Choy L, Skillington J, Derynck R. Roles of autocrine TGF-beta receptor and Smad signaling in adipocyte differentiation. J Cell Biol. 2000;149:667-82 pubmed
product information
Catalog Number :
12638
Product Name :
LPCX Smad3
article :
doi10.1083/jcb.149.3.667
id943
pubmed_id10791980
bacterial resistance :
Ampicillin
cloning :
backboneLPCX
backbone_mutation
backbone_origin
backbone_size6600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
LPCX was made by replacing the neo gene of LNCX with the puro gene.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HpaI
cloning_site_5HpaI
promoter
sequencing_primer_3
sequencing_primer_5LNCX
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesHSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, hMAD-3, hSMAD3, mad3
geneSMAD3
id4088
genbank_ids
mutation
nameSmad3
shRNA_sequence
size1200
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
115
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA