This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK5F Smad3
catalog :
12625
citations: 5
Reference
Ishii S, Fujiwara T, Yagi H, Takeda N, Ando M, Yamauchi H, et al. A novel pathogenic variant located just upstream of the C-terminal Ser423-X-Ser425 phosphorylation motif in SMAD3 causing Loeys-Dietz syndrome. Mol Genet Genomic Med. 2023;11:e2257 pubmed publisher
Wen J, Jiao B, Tran M, Wang Y. Pharmacological Inhibition of S100A4 Attenuates Fibroblast Activation and Renal Fibrosis. Cells. 2022;11: pubmed publisher
Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, et al. Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk. PLoS Genet. 2018;14:e1007681 pubmed publisher
Chavez R, Coricor G, Perez J, Seo H, Serra R. SOX9 protein is stabilized by TGF-β and regulates PAPSS2 mRNA expression in chondrocytes. Osteoarthritis Cartilage. 2017;25:332-340 pubmed publisher
Zhang Y, Feng X, Derynck R. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature. 1998;394:909-13 pubmed
product information
Catalog Number :
12625
Product Name :
pRK5F Smad3
article :
doi10.1038/29814
id941
pubmed_id9732876
bacterial resistance :
Ampicillin
cloning :
backbonepRK5
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
See author's map for details.
origin :
37
pi :
alt_names
MADR3
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5ClaI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, hMAD-3, hSMAD3, mad3
geneSMAD3
id4088
genbank_ids
mutation
nameSmad3
shRNA_sequence
size1275
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
115
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA