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product summary
company name :
Addgene
product type :
cDNA
product name :
GFP-rab7 WT
catalog :
12605
citations: 51
Reference
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Jeckel P, Kriebel M, Volkmer H. Autism Spectrum Disorder Risk Factor Met Regulates the Organization of Inhibitory Synapses. Front Mol Neurosci. 2021;14:659856 pubmed publisher
Mao M, Chang C, Pickar Oliver A, Cervia L, Wang L, Ji J, et al. Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo. Adv Biosyst. 2020;4:e2000059 pubmed publisher
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Akin E, Higerd G, Mis M, Tanaka B, Adi T, Liu S, et al. Building sensory axons: Delivery and distribution of NaV1.7 channels and effects of inflammatory mediators. Sci Adv. 2019;5:eaax4755 pubmed publisher
Joshi D, Zhang C, Babujee L, Vevea J, August B, Sheng Z, et al. Inappropriate Intrusion of an Axonal Mitochondrial Anchor into Dendrites Causes Neurodegeneration. Cell Rep. 2019;29:685-696.e5 pubmed publisher
Xie Y, Niu M, Ji C, Huang T, Zhang C, Tian Y, et al. SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Aβ Accumulation and Memory Deficits in an AD Mouse. Front Cell Neurosci. 2019;13:410 pubmed publisher
Shlevkov E, Basu H, Bray M, Sun Z, Wei W, Apaydin K, et al. A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport. Cell Rep. 2019;28:3224-3237.e5 pubmed publisher
Kim M, Zhong Y, Jung K, Chai Y, Binas B. Basal-type lumenogenesis in extraembryonic endoderm stem cells models the early visceral endoderm. J Cell Sci. 2019;132: pubmed publisher
Prokšová P, Lipov J, Zelenka J, Hunter E, Langerová H, Rumlova M, et al. Mason-Pfizer Monkey Virus Envelope Glycoprotein Cycling and Its Vesicular Co-Transport with Immature Particles. Viruses. 2018;10: pubmed publisher
Melamed J, Ioele S, Hannum A, Ullman V, Day E. Polyethylenimine-Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells. Mol Pharm. 2018;15:5135-5145 pubmed publisher
Williams E, Glauser L, Tsika E, Jiang H, Islam S, Moore D. Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting. Hum Mol Genet. 2018;27:3189-3205 pubmed publisher
Saridaki T, Nippold M, Dinter E, Roos A, Diederichs L, Fensky L, et al. FYCO1 mediates clearance of α-synuclein aggregates through a Rab7-dependent mechanism. J Neurochem. 2018;146:474-492 pubmed publisher
Steger M, Diez F, Dhekne H, Lis P, Nirujogi R, Karayel Ö, et al. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. elife. 2017;6: pubmed publisher
Guzman R, Bungert Plümke S, Franzen A, Fahlke C. Preferential association with ClC-3 permits sorting of ClC-4 into endosomal compartments. J Biol Chem. 2017;292:19055-19065 pubmed publisher
Yap C, Digilio L, McMahon L, Winckler B. The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes. Sci Rep. 2017;7:10481 pubmed publisher
Zhang X, Jiang S, Mitok K, Li L, Attie A, Martin T. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. J Cell Biol. 2017;216:2151-2166 pubmed publisher
Aoyama M, Yoshioka Y, Arai Y, Hirai H, Ishimoto R, Nagano K, et al. Intracellular trafficking of particles inside endosomal vesicles is regulated by particle size. J Control Release. 2017;260:183-193 pubmed publisher
Su T, Bai J, Chen Y, WANG X, Fu X, Li T, et al. An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro. Front Pharmacol. 2017;8:227 pubmed publisher
Solek C, Feng S, Perin S, Weinschutz Mendes H, Ekker M. Lineage tracing of dlx1a/2a and dlx5a/6a expressing cells in the developing zebrafish brain. Dev Biol. 2017;427:131-147 pubmed publisher
Chang C, Bijian K, Qiu D, Su J, Saad A, Dahabieh M, et al. Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells. Oncotarget. 2017;8:31199-31214 pubmed publisher
Machitani M, Sakurai F, Wakabayashi K, Nakatani K, Tachibana M, Mizuguchi H. MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2. J Virol. 2017;91: pubmed publisher
Ruhe F, Olling A, Abromeit R, Rataj D, Grieschat M, Zeug A, et al. Overexpression of the Endosomal Anion/Proton Exchanger ClC-5 Increases Cell Susceptibility toward Clostridium difficile Toxins TcdA and TcdB. Front Cell Infect Microbiol. 2017;7:67 pubmed publisher
Westcott N, Fernandez J, Molina H, Hang H. Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress. Nat Chem Biol. 2017;13:302-308 pubmed publisher
Najjar K, Erazo Oliveras A, Brock D, Wang T, Pellois J. An l- to d-Amino Acid Conversion in an Endosomolytic Analog of the Cell-penetrating Peptide TAT Influences Proteolytic Stability, Endocytic Uptake, and Endosomal Escape. J Biol Chem. 2017;292:847-861 pubmed publisher
Swaminathan G, Zhu W, Plowey E. BECN1/Beclin 1 sorts cell-surface APP/amyloid ? precursor protein for lysosomal degradation. Autophagy. 2016;12:2404-2419 pubmed
Schwenk B, Hartmann H, Serdaroglu A, Schludi M, Hornburg D, Meissner F, et al. TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons. EMBO J. 2016;35:2350-2370 pubmed
Zemoura K, Trümpler C, Benke D. Lys-63-linked Ubiquitination of ?-Aminobutyric Acid (GABA), Type B1, at Multiple Sites by the E3 Ligase Mind Bomb-2 Targets GABAB Receptors to Lysosomal Degradation. J Biol Chem. 2016;291:21682-21693 pubmed
Dinter E, Saridaki T, Nippold M, Plum S, Diederichs L, Komnig D, et al. Rab7 induces clearance of ?-synuclein aggregates. J Neurochem. 2016;138:758-74 pubmed publisher
Zheng Q, Zheng X, Zhang L, Luo H, Qian L, Fu X, et al. The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death. Mol Neurobiol. 2017;54:4189-4200 pubmed publisher
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Volpicelli Daley L, Gamble K, Schultheiss C, Riddle D, West A, Lee V. Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes. Mol Biol Cell. 2014;25:4010-23 pubmed publisher
Kim K, Jun Y, Park Y, Lee J, Suh B, Lim C, et al. Intracellular membrane association of the Aplysia cAMP phosphodiesterase long and short forms via different targeting mechanisms. J Biol Chem. 2014;289:25797-811 pubmed publisher
Kleemann B, Loos B, Scriba T, Lang D, Davids L. St John's Wort (Hypericum perforatum L.) photomedicine: hypericin-photodynamic therapy induces metastatic melanoma cell death. PLoS ONE. 2014;9:e103762 pubmed publisher
Romao S, Gasser N, Becker A, Guhl B, Bajagic M, Vanoaica D, et al. Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing. J Cell Biol. 2013;203:757-66 pubmed publisher
Stafa K, Tsika E, Moser R, Musso A, Glauser L, Jones A, et al. Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily. Hum Mol Genet. 2014;23:2055-77 pubmed publisher
Boukany P, Wu Y, Zhao X, Kwak K, Glazer P, Leong K, et al. Nonendocytic delivery of lipoplex nanoparticles into living cells using nanochannel electroporation. Adv Healthc Mater. 2014;3:682-9 pubmed publisher
Friedman J, DiBenedetto J, West M, Rowland A, Voeltz G. Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature. Mol Biol Cell. 2013;24:1030-40 pubmed publisher
Kalia M, Khasa R, Sharma M, Nain M, Vrati S. Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism. J Virol. 2013;87:148-62 pubmed publisher
Ramonet D, Podhajska A, Stafa K, Sonnay S, Trancikova A, Tsika E, et al. PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Hum Mol Genet. 2012;21:1725-43 pubmed publisher
Johnson C, Kannan T, Baseman J. Cellular vacuoles induced by Mycoplasma pneumoniae CARDS toxin originate from Rab9-associated compartments. PLoS ONE. 2011;6:e22877 pubmed publisher
Balut C, Gao Y, Murray S, Thibodeau P, Devor D. ESCRT-dependent targeting of plasma membrane localized KCa3.1 to the lysosomes. Am J Physiol Cell Physiol. 2010;299:C1015-27 pubmed publisher
Choudhury A, Dominguez M, Puri V, Sharma D, Narita K, Wheatley C, et al. Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells. J Clin Invest. 2002;109:1541-50 pubmed
product information
Catalog Number :
12605
Product Name :
GFP-rab7 WT
article :
doi10.1172/JCI15420
id934
pubmed_id12070301
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C1
backbone_mutation
backbone_originClontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
GFP-rab7 wild type
cloning
clone_methodRestriction Enzyme
cloning_site_3BAMHI
cloning_site_5BAMHI
promoter
sequencing_primer_3SV40pA-R
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCMT2B, PRO2706, RAB7
geneRAB7A
id7879
genbank_ids
NM_004637
mutation
nameRAB7 (Homo sapiens)
shRNA_sequence
size693
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGFP
locationN terminal on insert
tagHA
plasmid copy :
IMAGE Clone collection at ATCC
resistance markers :
377
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA