This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-EGFP-Cdc42(T17N)
catalog :
12601
citations: 8
Reference
Yu Y, Yoshimura S. Self-assembly of CIP4 drives actin-mediated asymmetric pit-closing in clathrin-mediated endocytosis. Nat Commun. 2023;14:4602 pubmed publisher
Medina C, Ferreira E, Bonifácio B, Mortara R, Bonfim Melo A. Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages. Microbes Infect. 2021;:104837 pubmed publisher
Bonfim Melo A, Ferreira d, Mortara R. Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. Front Microbiol. 2018;9:360 pubmed publisher
Chang F, Kim J, Choi Y, Park K. MTA promotes chemotaxis and chemokinesis of immune cells through distinct calcium-sensing receptor signaling pathways. Biomaterials. 2018;150:14-24 pubmed publisher
Chou Y, Cuevas C, Carocci M, Stubbs S, Ma M, Cureton D, et al. Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol. 2016;90:4494-4510 pubmed publisher
Sumida G, Yamada S. Rho GTPases and the downstream effectors actin-related protein 2/3 (Arp2/3) complex and myosin II induce membrane fusion at self-contacts. J Biol Chem. 2015;290:3238-47 pubmed publisher
Baschieri F, Confalonieri S, Bertalot G, Di Fiore P, Dietmaier W, Leist M, et al. Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Nat Commun. 2014;5:4839 pubmed publisher
Nalbant P, Hodgson L, Kraynov V, Toutchkine A, Hahn K. Activation of endogenous Cdc42 visualized in living cells. Science. 2004;305:1615-9 pubmed
product information
Catalog Number :
12601
Product Name :
pcDNA3-EGFP-Cdc42(T17N)
article :
doi10.1126/science.1100367
id931
pubmed_id15361624
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Cdc42 Dominant Negative
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5HindIII
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCDC42Hs, G25K, TKS
geneCDC42
id998
genbank_ids
mutationT17N
nameEGFP-Cdc42 (T17N)
shRNA_sequence
size1300
species
9606
Homo sapiens
tags
locationN terminal on insert
tagEGFP
resistance markers :
185
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA