This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-EGFP-Cdc42(wt)
catalog :
12599
citations: 11
Reference
Liu L, Sui R, Li L, Zhang L, Zeng D, Ni X, et al. Light Activates Cdc42-Mediated Needle-Shaped Filopodia Formation via the Integration of Small GTPases. Cell Mol Bioeng. 2022;15:599-609 pubmed publisher
Sasaki S, Takahashi R, Luo Y, Chujo K, Sera T, Kudo S. Spatiotemporal distribution of PKCα, Cdc42, and Rac1 before directed cell migration. Biochem Biophys Res Commun. 2021;584:26-31 pubmed publisher
Medina C, Ferreira E, Bonifácio B, Mortara R, Bonfim Melo A. Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages. Microbes Infect. 2021;:104837 pubmed publisher
Liu L, Jiang H, Zhao W, Meng Y, Li J, Huang T, et al. Cdc42-mediated supracellular cytoskeleton induced cancer cell migration under low shear stress. Biochem Biophys Res Commun. 2019;519:134-140 pubmed publisher
Bonfim Melo A, Ferreira d, Mortara R. Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. Front Microbiol. 2018;9:360 pubmed publisher
Chou Y, Cuevas C, Carocci M, Stubbs S, Ma M, Cureton D, et al. Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol. 2016;90:4494-4510 pubmed publisher
Muccioli M, Qaisi D, Herman K, Plageman T. Lens placode planar cell polarity is dependent on Cdc42-mediated junctional contraction inhibition. Dev Biol. 2016;412:32-43 pubmed publisher
Sumida G, Yamada S. Rho GTPases and the downstream effectors actin-related protein 2/3 (Arp2/3) complex and myosin II induce membrane fusion at self-contacts. J Biol Chem. 2015;290:3238-47 pubmed publisher
Baschieri F, Confalonieri S, Bertalot G, Di Fiore P, Dietmaier W, Leist M, et al. Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Nat Commun. 2014;5:4839 pubmed publisher
Jagan I, Fatehullah A, Deevi R, Bingham V, Campbell F. Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy. Oncogene. 2013;32:1305-15 pubmed publisher
Nalbant P, Hodgson L, Kraynov V, Toutchkine A, Hahn K. Activation of endogenous Cdc42 visualized in living cells. Science. 2004;305:1615-9 pubmed
product information
Catalog Number :
12599
Product Name :
pcDNA3-EGFP-Cdc42(wt)
article :
doi10.1126/science.1100367
id931
pubmed_id15361624
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Cdc42
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5HindIII
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5EGFP-C
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCDC42Hs, G25K, TKS
geneCDC42
id998
genbank_ids
mutation
nameEGFP-Cdc42 (WT)
shRNA_sequence
size1300
species
9606
Homo sapiens
tags
locationN terminal on insert
tagEGFP
resistance markers :
185
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA